Evidence map›Paper›PMID 35686023›Full record

ArticleFrontiers in aging neuroscience2022

Time-Varying Effective Connectivity for Describing the Dynamic Brain Networks of Post-stroke Rehabilitation.

Fangzhou Xu, Yuandong Wang, Han Li, Xin Yu, Chongfeng Wang, Ming Liu, Lin Jiang, Chao Feng, Jianfei Li, Dezheng Wang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. [Gait event-driven dynamic changes in brain-muscle networks and neuromuscular coordination mechanisms].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
    Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Fangzhou XuInternational School for Optoelectronic Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Yuandong WangInternational School for Optoelectronic Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Han LiInternational School for Optoelectronic Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Xin YuInternational School for Optoelectronic Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Chongfeng WangInternational School for Optoelectronic Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Ming LiuInternational School for Optoelectronic Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Lin JiangThe Clinical Hospital of Chengdu Brain Science Institute, Ministry of Education Key Lab for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China.
Chao FengInternational School for Optoelectronic Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Jianfei LiInternational School for Optoelectronic Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Dezheng WangThe Department of Physical Medicine and Rehabilitation, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Zhiguo YanSchool of Electrical Engineering and Automation, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Yang ZhangThe Department of Physical Medicine and Rehabilitation, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Jiancai LengInternational School for Optoelectronic Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Qilu University of Technology · CNShandong Academy of Sciences · CNQilu Hospital of Shandong University · CNUniversity of Electronic Science and Technology of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemiplegia is a common motor dysfunction caused by a stroke. However, the dynamic network mechanism of brain processing information in post-stroke hemiplegic patients has not been revealed when performing motor imagery (MI) tasks. We acquire electroencephalography (EEG) data from healthy subjects and post-stroke hemiplegic patients and use the Fugl-Meyer assessment (FMA) to assess the degree of motor function damage in stroke patients. Time-varying MI networks are constructed using the adaptive directed transfer function (ADTF) method to explore the dynamic network mechanism of MI in post-stroke hemiplegic patients. Finally, correlation analysis has been conducted to study potential relationships between global efficiency and FMA scores. The performance of our proposed method has shown that the brain network pattern of stroke patients does not significantly change from laterality to bilateral symmetry when performing MI recognition. The main change is that the contralateral motor areas of the brain damage and the effective connection between the frontal lobe and the non-motor areas are enhanced, to compensate for motor dysfunction in stroke patients. We also find that there is a correlation between FMA scores and global efficiency. These findings help us better understand the dynamic brain network of patients with post-stroke when processing MI information. The network properties may provide a reliable biomarker for the objective evaluation of the functional rehabilitation diagnosis of stroke patients.

Indexed as

Fugl-Meyer assessmentgraph theorymotor imagerystroketime-varying network

Identifiers

PMID35686023
PMCPMC9171495
OpenAlexW4281384848

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.