Evidence map›Paper›PMID 35685866›Full record

ArticlePathology oncology research : POR2022

Prognostic Analysis of Differentially Expressed DNA Damage Repair Genes in Bladder Cancer.

Yong Yang, Jieqing Yu, Yuanping Xiong, Jiansheng Xiao, Daofeng Dai, Feng Zhang

Open access · goldAbstract read
In one paragraph

Article in Pathology oncology research : POR, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yong YangDepartment of Otolaryngology Head and Neck Surgery, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, China.
Jieqing YuOtorhinolaryngology Head and Neck Surgery Institute, Department of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Yuanping XiongOtorhinolaryngology Head and Neck Surgery Institute, Department of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Jiansheng XiaoDepartment of General Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Daofeng DaiOtorhinolaryngology Head and Neck Surgery Institute, Department of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Feng ZhangThe National Engineering Research Center for Bioengineering Drugs and the Technologies, The Institute of Translational Medicine, Nanchang University, Nanchang, China.
Nanchang University · CNJiangxi Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bladder cancer (BCa) is the tenth most common tumor in humans. DNA damage repair genes (DDRGs) play important roles in many malignant tumors; thus, their functions in BCa should also be explored. We performed a comprehensive analysis of the expression profiles of DDRGs in 410 BCa tumors and 19 normal tissues from The Cancer Genome Atlas database. We identified 123 DDRGs differentially expressed between BCa tumors and normal tissues, including 95 upregulated and 28 downregulated genes. We detected 22 DDRGs associated with overall survival (OS) of patients with BCa by performing univariate Cox regression analysis. To explore the interactions between OS-associated DDRGs, we constructed a PPI network, which showed that the top six DDRGs (

Indexed as

Urinary Bladder NeoplasmsBiomarkers, TumorDNA DamageGene Expression Regulation, NeoplasticHistone DeacetylasesHumansPrognosisBiomarkers, TumorHDAC10 protein, humanHistone Deacetylasesbiomarkersbladder cancerdifferentially expressed genesDNA damage repair genesprognosis

Identifiers

PMID35685866
PMCPMC9172279
OpenAlexW4281383299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.