ArticleChemical science2022
Engineering lanmodulin's selectivity for actinides over lanthanides by controlling solvent coordination and second-sphere interactions.
Article in Chemical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 47 citations in OpenAlex.
- A family portrait of lanmodulin selectivity for enhanced rare-earth separations.Nature chemical biology · 2026Article
- Urban Biomining of Rare Earth Elements: Current Status and Future Opportunities.ACS environmental Au · 2026Review
- X-ray absorption spectroscopy of lanmodulin-derived peptides bound to rare earth elements.Journal of synchrotron radiation · 2025Article
- Cerium-mediated site-selective cysteine functionalization.Chemical science · 2025Article
- Computationally derived structural insights into Rare Earth selectivity in lanmodulin and its variants.Computational and structural biotechnology journal · 2025Article
- Article
- Insights into rare earth element speciation: unraveling sulfate and hydrolysis complexes through DFT calculations.Journal of molecular modeling · 2024Article
- Biogeochemistry of Actinides: Recent Progress and Perspective.ACS environmental Au · 2024Review
- Single-point mutated lanmodulin as a high-performance MRI contrast agent for vascular and kidney imaging.Nature communications · 2024Article
- Amino Acid Decorated Phenanthroline Diimide as Sustainable Hydrophilic Am(III) Masking Agent with High Acid Resistance.JACS Au · 2024Article
- Lanmodulin's EF 2-3 Domain: Insights from Infrared Spectroscopy and Simulations.ACS chemical biology · 2024Article
- Rare Earths-The Answer to Everything.Molecules (Basel, Switzerland) · 2024Review
- Recovery of rare earth elements from low-grade coal fly ash using a recyclable protein biosorbent.Frontiers in bioengineering and biotechnology · 2024Article
- Radiochemistry: A Hot Field with Opportunities for Cool Chemistry.ACS central science · 2023Review
- Radiolabeling andRSC chemical biology · 2023Article
- Article
- Lanthanides as Calcium Mimetic Species in Calcium-Signaling/Buffering Proteins: The Effect of Lanthanide Type on the CaInternational journal of molecular sciences · 2023Article
- A genetically encoded fluorescent sensor for manganese(II), engineered from lanmodulin.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Developing chelators that combine high affinity and selectivity for lanthanides and/or actinides is paramount for numerous industries, including rare earths mining, nuclear waste management, and cancer medicine. In particular, achieving selectivity between actinides and lanthanides is notoriously difficult. The protein lanmodulin (LanM) is one of Nature's most selective chelators for trivalent actinides and lanthanides. However, mechanistic understanding of LanM's affinity and selectivity for f-elements remains limited. In order to decipher, and possibly improve, the features of LanM's metal-binding sites that contribute to this actinide/lanthanide selectivity, we characterized five LanM variants, substituting the aspartate residue at the 9
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Registered trials
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