Evidence map›Paper›PMID 35685696›Full record

ArticleRSC advances2022

Antiviral activity of chitosan nanoparticles encapsulating silymarin (Sil-CNPs) against SARS-CoV-2 (

Samah A Loutfy, Ahmed I Abdel-Salam, Yassmin Moatasim, Mokhtar R Gomaa, Nasra F Abdel Fattah, Merna H Emam, Fedaa Ali, Hasnaa A ElShehaby, Eman A Ragab, Hanaa M Alam El-Din and 3 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Samah A LoutfyVirology and Immunology Unit, Cancer Biology Department, National Cancer Institute (NCI), Cairo University Fom El-Khalig 11796 Cairo Egypt samahloutfy@cu.edu.eg hanaa.alameldin@nci.cu.edu.eg.
Ahmed I Abdel-SalamNanotechnology Research Center (NTRC), The British University in Egypt El-Shorouk City, Suez Desert Road P. O. Box 43 Cairo 11837 Egypt Amal.Kasry@bue.edu.eg.
Yassmin MoatasimCenter of Scientific Excellence for Influenza Viruses, National Research Centre (NRC) Giza 12622 Egypt.ORCID https://orcid.org/0000-0003-2159-2511
Mokhtar R GomaaCenter of Scientific Excellence for Influenza Viruses, National Research Centre (NRC) Giza 12622 Egypt.
Nasra F Abdel FattahVirology and Immunology Unit, Cancer Biology Department, National Cancer Institute (NCI), Cairo University Fom El-Khalig 11796 Cairo Egypt samahloutfy@cu.edu.eg hanaa.alameldin@nci.cu.edu.eg.ORCID https://orcid.org/0000-0002-1462-037X
Merna H EmamNanotechnology Research Center (NTRC), The British University in Egypt El-Shorouk City, Suez Desert Road P. O. Box 43 Cairo 11837 Egypt Amal.Kasry@bue.edu.eg.
Fedaa AliNanotechnology Research Center (NTRC), The British University in Egypt El-Shorouk City, Suez Desert Road P. O. Box 43 Cairo 11837 Egypt Amal.Kasry@bue.edu.eg.
Hasnaa A ElShehabyBiochemistry Dept, Faculty of Science, Cairo University Egypt.
Eman A RagabBiochemistry Dept, Faculty of Science, Cairo University Egypt.
Hanaa M Alam El-DinVirology and Immunology Unit, Cancer Biology Department, National Cancer Institute (NCI), Cairo University Fom El-Khalig 11796 Cairo Egypt samahloutfy@cu.edu.eg hanaa.alameldin@nci.cu.edu.eg.
Ahmed MostafaCenter of Scientific Excellence for Influenza Viruses, National Research Centre (NRC) Giza 12622 Egypt.ORCID https://orcid.org/0000-0002-2878-5714
Mohamed A AliCenter of Scientific Excellence for Influenza Viruses, National Research Centre (NRC) Giza 12622 Egypt.
Amal KasryNanotechnology Research Center (NTRC), The British University in Egypt El-Shorouk City, Suez Desert Road P. O. Box 43 Cairo 11837 Egypt Amal.Kasry@bue.edu.eg.
Cairo University · EGBritish University in Egypt · EGNational Research Centre · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To develop a specific treatment against COVID-19, we investigated silymarin-chitosan nanoparticles (Sil-CNPs) as an antiviral agent against SARS-CoV-2 using

Identifiers

PMID35685696
PMCPMC9132606
OpenAlexW4282914501

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.