Evidence map›Paper›PMID 35685666›Full record

ArticleContrast media & molecular imaging2022

Effects of Naltrexone on Expression of Lipid Metabolism-Related Proteins in Liver Steatosis Induced by Endoplasmic Reticulum Stress in Mice.

Ping Yang, Leyao Xiao, Fei Zhao, Wei He, Guijuan Zhang, Yongjing Tang, Yinghua Chen, Qijiao Cheng, Yihuai He

Open access · hybridAbstract read
In one paragraph

Article in Contrast media & molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ping Yang *Department of Infectious Diseases, Affiliated Hospital of Zunyi Medical University, Zunyi 56300, China.
Leyao Xiao *School of Nursing, Zunyi Medical University, Zunyi 56300, China.
Fei ZhaoSchool of Nursing, Zunyi Medical University, Zunyi 56300, China.
Wei HeClinical College of Zunyi Medical University, Zunyi 56300, China.
Guijuan ZhangClinical College of Zunyi Medical University, Zunyi 56300, China.
Yongjing TangClinical College of Zunyi Medical University, Zunyi 56300, China.
Yinghua ChenDepartment of Infectious Diseases, Affiliated Hospital of Zunyi Medical University, Zunyi 56300, China.ORCID 0000-0001-7268-9108
Qijiao ChengDepartment of Infectious Diseases, Affiliated Hospital of Zunyi Medical University, Zunyi 56300, China.
Yihuai HeDepartment of Infectious Diseases, Affiliated Hospital of Zunyi Medical University, Zunyi 56300, China.ORCID 0000-0002-8639-3436
Zunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to explore the effect of naltrexone on the expression of lipid metabolism-related proteins in liver steatosis induced by endoplasmic reticulum stress in mice. Thirty inbred mice (C57BL/6J) were divided into three groups: group A (normal control group), group B (model control), and group C (naltrexone group). The male mice in group A were fed a regular diet, and the mice in groups B and C were fed a high-fat diet. Liver steatosis was observed by histopathological sections. Mouse liver (alanine aminotransferase (ALT) and triglyceride (TC)) content (glucose regulatory protein (GRP78), endoplasmic reticulum transmembrane protein kinase-1

Indexed as

Fatty LiverLipid MetabolismAnimalsCaspase 12Endoplasmic Reticulum StressMaleMiceMice, Inbred C57BLNaltrexoneProto-Oncogene Proteins c-bcl-2Caspase 12NaltrexoneProto-Oncogene Proteins c-bcl-2

Identifiers

PMID35685666
PMCPMC9168111
OpenAlexW4281623511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.