Evidence map›Paper›PMID 35685661›Full record

Trial reportContrast media & molecular imaging2022

Effect of Berberine Hydrochloride on the Diversity of Intestinal Flora in Parkinson's Disease Patients.

Jiaojiao Li, Pin Meng, Jianyu Zhang, Mingli He

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Contrast media & molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jiaojiao LiThe First People's Hospital of Lianyungang, The First Affiliated Hospital of KangDA College of Nanjing Medical University, Lianyungang 222000, Jiangsu Province, China.
Pin MengThe First People's Hospital of Lianyungang, The First Affiliated Hospital of KangDA College of Nanjing Medical University, Lianyungang 222000, Jiangsu Province, China.
Jianyu ZhangThe First People's Hospital of Lianyungang, The First Affiliated Hospital of KangDA College of Nanjing Medical University, Lianyungang 222000, Jiangsu Province, China.
Mingli HeThe First People's Hospital of Lianyungang, The First Affiliated Hospital of KangDA College of Nanjing Medical University, Lianyungang 222000, Jiangsu Province, China.ORCID 0000-0002-1052-6351
The First People’s Hospital of Lianyungang · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the effect of berberine hydrochloride on the diversity of intestinal flora in patients with Parkinson's disease (PD). Prospectively selected 68 PD patients, admitted to our hospital from April 2021 to June 2021, were randomly assigned to an observation group and a control group (

Indexed as

BerberineGastrointestinal MicrobiomeParkinson DiseaseHumansInterleukin-6Interleukin-8RNA, Ribosomal, 16STumor Necrosis Factor-alphaBerberineInterleukin-6Interleukin-8RNA, Ribosomal, 16STumor Necrosis Factor-alpha

Identifiers

PMID35685661
PMCPMC9170458
OpenAlexW4281625455

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.