Evidence map›Paper›PMID 35685516›Full record

ArticleInternational journal of clinical practice2022

The Influence of Salt Sensitivity Phenotype on Sodium Excretion and Diuresis: A Chrononutrition Pilot Study.

Upeksha Sewwandi Alwis, Irina Verbakel, Kim Pauwaert, Joris Delanghe, Lien Dossche, John Van Camp, Saskia Roggeman, Karel Everaert

Open access · goldAbstract read
In one paragraph

Article in International journal of clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Upeksha Sewwandi AlwisDepartment of Human Structure and Repair, Ghent University, 9000 Ghent, Belgium.ORCID https://orcid.org/0000-0002-0244-5375
Irina VerbakelDepartment of Human Structure and Repair, Ghent University, 9000 Ghent, Belgium.
Kim PauwaertDepartment of Human Structure and Repair, Ghent University, 9000 Ghent, Belgium.
Joris DelangheDepartment of Diagnostic Sciences, Ghent University, 9000 Ghent, Belgium.
Lien DosscheDepartment of Internal Medicine and Pediatrics, Ghent University, 9000 Ghent, Belgium.
John Van CampDepartment of Food Technology, Safety and Health, Ghent University, 9000 Ghent, Belgium.
Saskia RoggemanResearch and Policy Department, Psychiatric Center Sint-Jan-Baptist, 9060 Zelzate, Belgium.
Karel EveraertDepartment of Human Structure and Repair, Ghent University, 9000 Ghent, Belgium.
Ghent University · BEGhent University Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chrononutrition studies on interaction of diet/nutrients on endogenous circadian clocks and meal timing on metabolic homeostasis may be of importance in the management of nocturnal polyuria (NP), owing to loss of circadian rhythm in nighttime urination. Dietary salt restriction is an increasingly popular lifestyle recommendation for NP patients. Aim: This study aims to evaluate the effect of an acute salt load on diuresis and to study the phenomenon of salt sensitivity. Results: Compared to 8 g, ingestion of 12 g of salt significantly increased diuresis after 4 hrs. Pure water load induced fast diuresis, whereas salt and water load initially reduced diuresis and promoted late increase in diuresis. The total voided volume was significantly lower in the salt sensitive individuals. Conclusion: Taken together, salt sensitivity profile and type and time of fluid intake are important considerations to build effective personalized lifestyle recommendations for NP patients, which needs further investigation.

Indexed as

HypertensionNocturiaDiuresisHumansPhenotypePilot ProjectsPolyuriaSodiumSodium Chloride, DietaryWaterSodiumSodium Chloride, DietaryWater

Identifiers

PMID35685516
PMCPMC9159230
OpenAlexW4210937418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.