Evidence map›Paper›PMID 35685485›Full record

ArticleInternational journal of clinical practice2022

A Large Retrospective Study of Epidemiological Characteristics of COVID-19 Patients in the North of Iran: Association between SARS-CoV-2 RT-PCR Ct Values with Demographic Data.

Farzin Sadeghi, Abazar Pournajaf, Mehrdad Halaji, Mohammad Chehrazi, Fatemeh Hejazi Amiri, Saghar Saber Amoli, Ali Hasanzadeh, Mostafa Javanian, Masoumeh Bayani, Mahmoud Sadeghi Haddad Zavareh and 28 more

Abstract read
In one paragraph

Article in International journal of clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Farzin Sadeghi *Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.ORCID https://orcid.org/0000-0001-8599-3643
Abazar Pournajaf *Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.ORCID https://orcid.org/0000-0002-6753-5953
Mehrdad Halaji *Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.ORCID https://orcid.org/0000-0002-4576-8203
Mohammad ChehraziDepartment of Biostatistics and Epidemiology, School of Public Health, Babol University of Medical Sciences, Babol, Iran.
Fatemeh Hejazi AmiriDepartment of Medical Microbiology, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran.ORCID https://orcid.org/0000-0001-5427-9594
Saghar Saber AmoliDepartment of Medical Microbiology, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran.ORCID https://orcid.org/0000-0002-4246-0852
Ali HasanzadehDepartment of Medical Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
Mostafa JavanianInfectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Masoumeh BayaniInfectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Mahmoud Sadeghi Haddad ZavarehInfectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Mehran ShokriInfectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Arefeh BabazadehInfectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.ORCID https://orcid.org/0000-0002-1362-7203
Mohsen MohammadiNon-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Hamed MehdinezhadDepartment of Internal Medicine, Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.ORCID https://orcid.org/0000-0002-1049-1267
Mahmoud MonadiDepartment of Internal Medicine, Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.
Parviz Amri MalehDepartment of Anesthesiology, Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.ORCID https://orcid.org/0000-0003-2648-9820
Hamid Reza NouriCellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.ORCID https://orcid.org/0000-0002-8387-0807
Abdolreza DaraeiDepartment of Medical Genetics, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran.ORCID https://orcid.org/0000-0002-2106-835X
Mahdie Yousefnia PashaBabol Health Center, Babol University of Medical Sciences, Babol, Iran.ORCID https://orcid.org/0000-0003-0159-2813
Mehdi TouraniHealth Research Institute, Babol University of Medical Sciences, Babol, Iran.ORCID https://orcid.org/0000-0002-9379-780X
Seyed Raheleh AhmadianHealth Research Institute, Babol University of Medical Sciences, Babol, Iran.ORCID https://orcid.org/0000-0003-4481-6880
Nadia EsmailzadehDepartment of Medical Microbiology, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran.
Seyyedeh Maedeh MirtabarHealth Research Institute, Babol University of Medical Sciences, Babol, Iran.
Shakiba AsadiHealth Research Institute, Babol University of Medical Sciences, Babol, Iran.
Ebrahim NasiraiePart of Infectious Control, Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.
Nafiseh EzamiPart of Medical Records, Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.
Shahrbano GorjinejadPart of Infectious Control, Amirkola Hospital, Babol University of Medical Sciences, Babol, Iran.
Kobra FallhpourPart of Infectious Control, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran.
Fatemeh FakhraiePart of Infectious Control, Shahid Yahyanejad Hospital, Babol University of Medical Sciences, Babol, Iran.
Yousef BeheshtiDepartment of Medical Genetics, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran.
Mahnaz BaghershiroodiGenetics Laboratory, Shafizadeh Amirkola Children's Hospital, Babol University of Medical Sciences, Babol, Iran.
Faeze RastiHealth Research Institute, Babol University of Medical Sciences, Babol, Iran.
Maryam SalehiDepartment of Medical Microbiology, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran.
Atiyeh AleahmadDepartment of Clinical Biochemistry, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran.
Rahman BabapourBabol Health Center, Babol University of Medical Sciences, Babol, Iran.
Rahim MalekzadehBabol Health Center, Babol University of Medical Sciences, Babol, Iran.
Rahmat Habibzadeh KashiBabol Health Center, Babol University of Medical Sciences, Babol, Iran.
Yousef YahyapourCellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.ORCID https://orcid.org/0000-0002-8823-8042

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To avoid worsening from mild, moderate, and severe diseases and to reduce mortality, it is necessary to identify the subpopulation that is more vulnerable to the development of COVID-19 unfavorable consequences. This study aims to investigate the demographic information, prevalence rates of common comorbidities among negative and positive real-time reverse-transcriptase polymerase chain reaction (rRT-PCR) patients, and the association between SARS-CoV-2 cycle threshold (Ct) at hospital admission, demographic data, and outcomes of the patients in a large population in Northern Iran. Methods: This large retrospective cross-sectional study was performed from 7 March to 20 December 2020. Demographic data, including gender, age, underlying diseases, clinical outcomes, and Ct values, were obtained from 8,318 cases suspected of COVID-19, who were admitted to four teaching hospitals affiliated to Babol University of Medical Sciences (MUBABOL), in the north of Iran. Results: Since 7 March 2020, the data were collected from 8,318 cases suspected of COVID-19 (48.5% female and 51.5% male) with a mean age of 53 ± 25.3 years. Among 8,318 suspected COVID-19 patients, 3,250 (39.1%) had a positive rRT-PCR result; 1,632 (50.2%) patients were male and 335 (10.3%) patients died during their hospital stay. The distribution of positive rRT-PCR revealed that most patients (464 (75.7%)) had a Ct between 21 and 30 (Group B). Conclusion: Elderly patients, lower Ct, patients having at least one comorbidity, and male cases were significantly associated with increased risk for COVID-19-related mortality. Moreover, mortality was significantly higher in patients with diabetes, kidney disease, and respiratory disease.

Indexed as

COVID-19SARS-CoV-2AdultAgedCross-Sectional StudiesDemographyFemaleHumansIranMaleMiddle AgedRetrospective StudiesReverse Transcriptase Polymerase Chain Reaction

Identifiers

PMID35685485
PMCPMC9159227

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