Evidence map›Paper›PMID 35685320›Full record

ArticleKidney international reports2022

Nondirected Living Kidney Donation and Recipient Outcomes in the United States: A 20-Year Review.

Muhammad Y Jan, Muhammad S Yaqub, Oluwafisayo O Adebiyi, Tim E Taber, Melissa D Anderson, Dennis P Mishler, Heather N Burney, Yang Li, Xiaochun Li, Asif A Sharfuddin

Abstract read
In one paragraph

Article in Kidney international reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Muhammad Y JanDivision of Nephrology and Transplantation, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Muhammad S YaqubDivision of Nephrology and Transplantation, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Oluwafisayo O AdebiyiDivision of Nephrology and Transplantation, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Tim E TaberDivision of Nephrology and Transplantation, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Melissa D AndersonDivision of Nephrology and Transplantation, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Dennis P MishlerDivision of Nephrology and Transplantation, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Heather N BurneyDepartment of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Yang LiDepartment of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Xiaochun LiDepartment of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Asif A SharfuddinDivision of Nephrology and Transplantation, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Nondirected donation (NDD) of the kidneys is a growing practice where donors who do not have any genetic or emotional relationship are selected to donate to a wide variety of recipients with a range of selection criteria and decisions which are left up to individual transplant centers. Methods: We review all adult living kidney donor-recipient (DR) pairs and outcomes from NDDs who were recorded in United Network for Organ Sharing (UNOS) database as code 10 (anonymous) from October 1997 to September 2017 for demographics and outcomes. Results: A total of 2174 DR pairs were identified. The number of NDDs increased from 18 in 2000 to 256 in 2016. Survival analysis showed higher death-censored-graft survival (DC-GS) when recipient was 20 years or more older than donor followed by recipient-donor within 20 years of age and lowest when donor was 20 years or more older than recipient ( Conclusion: Overall, the number of NDDs has increased significantly in the 20-year review period. Transplants from NDDs have excellent long-term outcomes. Better matching of controllable DR factors, such as age and body mass index (BMI), could further improve GS. Further research is needed to incorporate these DR factors into paired kidney donation programs potentially enhancing the utility and beneficence of this invaluable donation.

Indexed as

donor-recipient matchingliving kidney donationnondirected kidney donationpaired exchange

Identifiers

PMID35685320
PMCPMC9171626

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.