Evidence map›Paper›PMID 35685319›Full record

ArticleKidney international reports2022

The International IgA Nephropathy Network Prediction Tool Underestimates Disease Progression in Indian Patients.

Soumita Bagchi, Ashish Datt Upadhyay, Adarsh Barwad, Geetika Singh, Arunkumar Subbiah, Raj Kanwar Yadav, Sandeep Mahajan, Dipankar Bhowmik, Sanjay Kumar Agarwal

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. IgA nephropathy management: what does the future hold?Kidney international supplements · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Soumita BagchiDepartment of Nephrology, All India Institute of Medical Sciences, New Delhi, India.
Ashish Datt UpadhyayDepartment of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.
Adarsh BarwadDepartment of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Geetika SinghDepartment of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Arunkumar SubbiahDepartment of Nephrology, All India Institute of Medical Sciences, New Delhi, India.
Raj Kanwar YadavDepartment of Nephrology, All India Institute of Medical Sciences, New Delhi, India.
Sandeep MahajanDepartment of Nephrology, All India Institute of Medical Sciences, New Delhi, India.
Dipankar BhowmikDepartment of Nephrology, All India Institute of Medical Sciences, New Delhi, India.
Sanjay Kumar AgarwalDepartment of Nephrology, All India Institute of Medical Sciences, New Delhi, India.
All India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: International IgA nephropathy (IgAN) network (IIgANN) prediction tool was developed to predict risk of progression in IgAN. We attempted to externally validate this tool in an Indian cohort because the original study did not include Indian patients. Methods: Adult patients with primary IgAN were stratified to low, intermediate, higher, and highest risk groups, as per the original model. Primary outcome was reduction in estimated glomerular filtration rate (eGFR) by >50% or kidney failure. Both models were evaluated using discrimination: concordance statistics (C-statistics), time-dependent receiver operating characteristic (ROC) curves, R Results: A total of 316 patients with median follow-up of 2.8 years had 87 primary outcome events. Both models with and without race showed reasonable discrimination (C-statistics 0.845 for both models, R Conclusion: IIgANN prediction tool showed reasonable discrimination of risk in Indian patients but underestimated the trajectory of disease progression across all risk groups.

Indexed as

IgA nephropathyIndiansoutcomeprediction equationriskvalidity

Identifiers

PMID35685319
PMCPMC9171624
OpenAlexW4221135643

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.