Evidence map›Paper›PMID 35684929›Full record

ArticleSensors (Basel, Switzerland)2022

An Analysis of Semicircular Channel Backscattering Interferometry through Ray Tracing Simulations.

Niall M C Mulkerns, William H Hoffmann, Ian D Lindsay, Henkjan Gersen

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Niall M C MulkernsH. H. Wills Physics Laboratory, University of Bristol, Bristol BS8 1TL, UK.ORCID 0000-0002-7839-5896
William H HoffmannH. H. Wills Physics Laboratory, University of Bristol, Bristol BS8 1TL, UK.ORCID 0000-0002-6689-2609
Ian D LindsayH. H. Wills Physics Laboratory, University of Bristol, Bristol BS8 1TL, UK.
Henkjan GersenH. H. Wills Physics Laboratory, University of Bristol, Bristol BS8 1TL, UK.ORCID 0000-0002-9253-7555

Funding

Engineering and Physical Sciences Research Council EP/L016648/1Engineering and Physical Sciences Research Council EP/R511663/1Engineering and Physical Sciences Research Council EP/R51245/X
6 · The paper itself

Abstract

Recent backscattering interferometry studies utilise a single channel microfluidic system, typically approximately semicircular in cross-section. Here, we present a complete ray tracing model for on-chip backscattering interferometry with a semicircular cross-section, including the dependence upon polarisation and angle of incidence. The full model is validated and utilised to calculate the expected fringe patterns and sensitivities observed under both normal and oblique angles of incidence. Comparison with experimental data from approximately semicircular channels using the parameters stated shows that they cannot be explained using a semicircular geometry. The disagreement does not impact on the validity of the experimental data, but highlights that the optical mechanisms behind the various modalities of backscattering interferometry would benefit from clarification. From the analysis presented here, we conclude that for reasons of ease of analysis, data quality, and sensitivity for a given radius, capillary-based backscattering interferometry affords numerous benefits over on-chip backscattering interferometry.

Indexed as

InterferometryMicrofluidicsbackscattering interferometrymicrofluidicsray tracingrefractive indexsemicircular channel

Identifiers

PMID35684929
PMCPMC9185450

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.