Evidence map›Paper›PMID 35684423›Full record

ArticleMolecules (Basel, Switzerland)2022

Dually Responsive Poly(

Veronika Kozlovskaya, Yiming Yang, Fei Liu, Kevin Ingle, Aftab Ahmad, Ganesh V Halade, Eugenia Kharlampieva

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Polymer vesicles for the delivery of inhibitors of cariogenic biofilm.Dental materials : official publication of the Academy of Dental Materials · 2024
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Veronika KozlovskayaDepartment of Chemistry, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Yiming YangDepartment of Chemistry, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Fei LiuDepartment of Chemistry, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Kevin IngleDepartment of Cardiovascular Diseases, School of Medicine, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0001-9420-8117
Aftab AhmadDepartment of Anesthesiology and Perioperative Medicine, School of Medicine, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0003-0686-0987
Ganesh V HaladeDivision of Cardiovascular Sciences, Department of Internal Medicine, University of South Florida, Tampa, FL 33602, USA.
Eugenia KharlampievaDepartment of Chemistry, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
University of Alabama at Birmingham · USUniversity of South Florida · US

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
National Science Foundation DMR Award 1608728NCI NIH HHS P30 CA013148
6 · The paper itself

Abstract

Limited tissue selectivity and targeting of anticancer therapeutics in systemic administration can produce harmful side effects in the body. Various polymer nano-vehicles have been developed to encapsulate therapeutics and prevent premature drug release. Dually responsive polymeric vesicles (polymersomes) assembled from temperature-/pH-sensitive block copolymers are particularly interesting for the delivery of encapsulated therapeutics to targeted tumors and inflamed tissues. We have previously demonstrated that temperature-responsive poly(

Indexed as

Drug CarriersPolymersAnimalsBiocompatible MaterialsCaprolactamDimethylpolysiloxanesDoxorubicinDrug Delivery SystemsMicebaysilonBiocompatible MaterialsCaprolactamDimethylpolysiloxanesDoxorubicinDrug CarriersPolymerspoly-N-vinylcaprolactamdegradablein-vivo toxicitypolymersomepoly(N-vinylcaprolactam)temperature-responsive

Identifiers

PMID35684423
PMCPMC9182360
OpenAlexW4281643438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.