Evidence map›Paper›PMID 35684419›Full record

ArticleMolecules (Basel, Switzerland)2022

Targeting Akt/NF-κB/p53 Pathway and Apoptosis Inducing Potential of 1,2-Benzenedicarboxylic Acid, Bis (2-Methyl Propyl) Ester Isolated from

Ajay Kumar, Sandeep Kaur, Sukhvinder Dhiman, Prithvi Pal Singh, Gaurav Bhatia, Sharad Thakur, Hardeep Singh Tuli, Upendra Sharma, Subodh Kumar, Abdulmajeed G Almutary and 5 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

  1. The Biochemical Role of Bitter Melon (Food science & nutrition · 2026
    Article
  2. Article
  3. Exploring the antibacterial potential ofFrontiers in pharmacology · 2025
    Article
  4. Evaluation of the Bioactive Compounds ofMolecules (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Chemopreventive Effects ofCurrent issues in molecular biology · 2023
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Ajay KumarDepartment of Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar 143005, India.
Sandeep KaurDepartment of Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar 143005, India.
Sukhvinder DhimanDepartment of Chemistry, Guru Nanak Dev University, Amritsar 143005, India.ORCID 0000-0001-7466-975X
Prithvi Pal SinghChemical Technology Division, CSIR-IHBT, Palampur 176061, India.
Gaurav BhatiaDepartment of Biochemistry, Pt. Jawaharlal Nehru Government Medical College and Hospital Chamba, Chamba 176310, India.
Sharad ThakurBiotechnology Division, COVID-19 Project, CSIR-IHBT, Palampur 176061, India.
Hardeep Singh TuliDepartment of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala 133207, India.ORCID 0000-0003-1155-0094
Upendra SharmaChemical Technology Division, CSIR-IHBT, Palampur 176061, India.ORCID 0000-0002-7693-8690
Subodh KumarDepartment of Chemistry, Guru Nanak Dev University, Amritsar 143005, India.
Abdulmajeed G AlmutaryDepartment of Medical Biotechnology, College of Applied Medical Sciences, Qassim University, Buraydah 52266, Saudi Arabia.ORCID 0000-0001-5709-4130
Abdullah M AlnuqaydanDepartment of Medical Biotechnology, College of Applied Medical Sciences, Qassim University, Buraydah 52266, Saudi Arabia.ORCID 0000-0001-9306-609X
Arif HussainSchool of Life Sciences, Manipal Academy of Higher Education, Dubai Campus, Dubai 345050, United Arab Emirates.ORCID 0000-0002-0851-4845
Shafiul HaqueResearch and Scientific Studies Unit, College of Nursing and Allied Health Sciences, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0002-2989-121X
Kuldeep DhamaDivision of Pathology, ICAR-Indian Veterinary Research Institute, Bareilly 243122, India.ORCID 0000-0001-7469-4752
Satwinderjeet KaurDepartment of Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar 143005, India.
Guru Nanak Dev University · INQassim University · SABursa Uludağ Üni̇versi̇tesi̇ · TRGovernment Medical College and Hospital · INMaharishi Markandeshwar University, Mullana · IN

Funding

Qassim University NA
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bone NeoplasmsBoraginaceaeOsteosarcomaApoptosisCell Line, TumorCell ProliferationEstersHumansMolecular Docking SimulationNF-kappa BProto-Oncogene Proteins c-aktTumor Suppressor Protein p53EstersNF-kappa BProto-Oncogene Proteins c-aktTumor Suppressor Protein p53antiproliferative activityapoptosis inductionG0/G1 phaseOnosma bracteataosteosarcomaROS

Identifiers

PMID35684419
PMCPMC9182111
OpenAlexW4281766060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.