Evidence map›Paper›PMID 35684414›Full record

ArticleMolecules (Basel, Switzerland)2022

Quinine Esters with 1,2-Azole, Pyridine and Adamantane Fragments.

Gulim K Mukusheva, Aigerym R Zhasymbekova, Roza B Seidakhmetova, Oralgazy A Nurkenov, Ekaterina A Akishina, Sergey K Petkevich, Evgenij A Dikusar, Vladimir I Potkin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Synthesis and Biological Activity ofMolecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gulim K MukushevaKaraganda Buketov University, Karaganda 100024, Kazakhstan.
Aigerym R ZhasymbekovaKaraganda Buketov University, Karaganda 100024, Kazakhstan.
Roza B SeidakhmetovaKaraganda Buketov University, Karaganda 100024, Kazakhstan.
Oralgazy A NurkenovInstitute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, Karaganda 100008, Kazakhstan.
Ekaterina A AkishinaInstitute of Physical Organic Chemistry, National Academy of Sciences of Belarus, 220072 Minsk, Belarus.ORCID 0000-0002-0803-8623
Sergey K PetkevichInstitute of Physical Organic Chemistry, National Academy of Sciences of Belarus, 220072 Minsk, Belarus.ORCID 0000-0001-7823-3208
Evgenij A DikusarInstitute of Physical Organic Chemistry, National Academy of Sciences of Belarus, 220072 Minsk, Belarus.
Vladimir I PotkinInstitute of Physical Organic Chemistry, National Academy of Sciences of Belarus, 220072 Minsk, Belarus.

Funding

Science Committee of the Ministry of Education and Science of the Republic of Kazakhstan project No. АР08855433
6 · The paper itself

Abstract

An efficient method of producing quinine derivatives via reaction of acylation with 4,5-dichloroisothiazole-3-, 5-arylisoxazole-3-, adamantane- and hydrochlorides of pyridine-3- and pyridine-4-carbonyl chlorides was developed. All synthesized compounds were tested for antiviral, antimicrobial and analgesic activity. The most pronounced antibacterial activity was shown by the compounds

Indexed as

AdamantaneAnalgesicsAnimalsAnti-Bacterial AgentsAzolesEstersPyridinesQuinineAdamantaneAnalgesicsAnti-Bacterial AgentsAzolesEstersPyridinesQuinineadamantaneanalgesic activityantimicrobial activityantiviral activityestersisothiazoleisoxazolepyridinequaternary pyridinium saltsquinine

Identifiers

PMID35684414
PMCPMC9182173

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.