Evidence map›Paper›PMID 35684308›Full record

ArticleMolecules (Basel, Switzerland)2022

Design, Synthesis, and In Vitro and In Vivo Antifungal Activity of Novel Triazoles Containing Phenylethynyl Pyrazole Side Chains.

Tingjunhong Ni, Zichao Ding, Fei Xie, Yumeng Hao, Junhe Bao, Jingxiang Zhang, Shichong Yu, Yuanying Jiang, Dazhi Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Tingjunhong NiDepartment of Pharmacy, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No. 1239 Siping Road, Shanghai 200092, China.
Zichao DingDepartment of Organic Chemistry, School of Pharmacy, Navy Medical University, No. 325 Guohe Road, Shanghai 200433, China.
Fei XieDepartment of Organic Chemistry, School of Pharmacy, Navy Medical University, No. 325 Guohe Road, Shanghai 200433, China.
Yumeng HaoDepartment of Organic Chemistry, School of Pharmacy, Navy Medical University, No. 325 Guohe Road, Shanghai 200433, China.
Junhe BaoDepartment of Organic Chemistry, School of Pharmacy, Navy Medical University, No. 325 Guohe Road, Shanghai 200433, China.
Jingxiang ZhangCenter for New Drug Research, School of Pharmacy, Navy Medical University, No. 325 Guohe Road, Shanghai 200433, China.
Shichong YuDepartment of Organic Chemistry, School of Pharmacy, Navy Medical University, No. 325 Guohe Road, Shanghai 200433, China.
Yuanying JiangDepartment of Pharmacy, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No. 1239 Siping Road, Shanghai 200092, China.
Dazhi ZhangDepartment of Pharmacy, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No. 1239 Siping Road, Shanghai 200092, China.
Tongji University · CN

Funding

Fundamental Research Funds for the Central Universities 22120210587National Natural Science Foundation of China 81830106National Natural Science Foundation of China 82020108032National Natural Science Foundation of China 82103991National Natural Science Foundation of China 82173786Science and Technology Commission of Shanghai Municipality 21S11901300
6 · The paper itself

Abstract

A series of triazole derivatives containing phenylethynyl pyrazole moiety as side chain were designed, synthesized, and most of them exhibited good in vitro antifungal activities. Especially, compounds

Indexed as

Antifungal AgentsCryptococcus neoformansAnimalsCandida albicansFluconazoleMiceMicrobial Sensitivity TestsPyrazolesStructure-Activity RelationshipTriazolesAntifungal AgentsFluconazolePyrazolesTriazolesantifungalCYP51molecular dockingsynthesistriazole

Identifiers

PMID35684308
PMCPMC9182106
OpenAlexW4281493678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.