Evidence map›Paper›PMID 35684116›Full record

ArticleNutrients2022

Prognostic Value of the Controlling Nutritional Status (CONUT) Score in Patients at Dialysis Initiation.

Kimiaki Takagi, Hiroshi Takahashi, Tomomi Miura, Kasumi Yamagiwa, Kota Kawase, Yuka Muramatsu-Maekawa, Takuya Koie, Masashi Mizuno

Abstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kimiaki TakagiDepartment of Urology, Daiyukai Daiichi Hospital, 1-6-12, Hagoromo, Ichinomiya 491-0025, Japan.
Hiroshi TakahashiDepartment of Nephrology, Fujita Health University School of Medicine, Toyoake 470-1192, Japan.
Tomomi MiuraDepartment of Nutrition, Daiyukai Daiichi Hospital, 1-6-12, Hagoromo, Ichinomiya 491-0025, Japan.
Kasumi YamagiwaDepartment of Nutrition, Daiyukai Daiichi Hospital, 1-6-12, Hagoromo, Ichinomiya 491-0025, Japan.
Kota KawaseDepartment of Urology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu 501-1193, Japan.
Yuka Muramatsu-MaekawaDepartment of Urology, Daiyukai Daiichi Hospital, 1-6-12, Hagoromo, Ichinomiya 491-0025, Japan.
Takuya KoieDepartment of Urology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu 501-1193, Japan.ORCID 0000-0002-2980-127X
Masashi MizunoRenal Replacement Therapy, Division of Nephrology, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya 166-8550, Japan.ORCID 0000-0003-3235-6880

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein-energy wasting (PEW) is common in patients with chronic kidney disease (CKD), and affects their prognosis. The Controlling Nutritional Status (CONUT) score is a nutritional screening tool calculated using only blood test data. This study aimed to investigate the prognostic value of CONUT score in patients just initiating dialysis. A total of 311 CKD patients who stably initiated dialysis were enrolled. Only 27 (8.7%) patients were classified as having normal nutritional status. The CONUT score was also independently correlated with elevated C-reactive protein levels (β = 0.485, p < 0.0001). During the median follow-up of 37 months, 100 patients (32.2%) died. The CONUT score was an independent predictor of all-cause mortality (adjusted hazard ratio 1.13, 95% confidence interval 1.04−1.22, p < 0.0024). As model discrimination, the addition of the CONUT score to a prediction model based on established risk factors significantly improved net reclassification improvement (0.285, p = 0.028) and integrated discrimination improvement (0.025, p = 0.023). The CONUT score might be a simplified surrogate marker of the PEW with clinical utility and could predict all-cause mortality, in addition to improving the predictability in CKD patients just initiating dialysis. The CONUT score also could predict infectious-disease mortality.

Indexed as

Nutritional StatusRenal Insufficiency, ChronicHumansNutrition AssessmentPrognosisRenal DialysisRetrospective Studieschronic kidney diseaseCONUTdialysismortalitynutritional assessmentprotein-energy wasting

Identifiers

PMID35684116
PMCPMC9182995

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.