Evidence map›Paper›PMID 35684014›Full record

Observational studyNutrients2022

Increased Breastfeeding Proportion Is Associated with Improved Gross Motor Skills at 3-5 Years of Age: A Pilot Study.

Erica E D'Souza, Rutvi Vyas, Michaela Sisitsky, Henry A Feldman, Borjan Gagoski, Jonathan Litt, Ryan J Larsen, Matthew J Kuchan, John B Lasekan, Brad P Sutton and 3 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Erica E D'SouzaDivision of Newborn Medicine, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0001-9848-8347
Rutvi VyasDivision of Newborn Medicine, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0001-7177-0721
Michaela SisitskyFetal-Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Boston, MA 02115, USA.
Henry A FeldmanDivision of Newborn Medicine, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0002-1748-0894
Borjan GagoskiFetal-Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0003-3777-2621
Jonathan LittDepartment of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.ORCID 0000-0002-8748-2449
Ryan J LarsenBeckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Matthew J KuchanAbbott Laboratories, Columbus, OH 43219, USA.
John B LasekanAbbott Laboratories, Columbus, OH 43219, USA.ORCID 0000-0002-0926-0576
Brad P SuttonBeckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0002-8443-0408
Patricia Ellen GrantDivision of Newborn Medicine, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0003-1005-4013
Yangming OuDivision of Newborn Medicine, Boston Children's Hospital, Boston, MA 02115, USA.
Sarah U MortonDivision of Newborn Medicine, Boston Children's Hospital, Boston, MA 02115, USA.ORCID 0000-0002-7816-2646
Boston Children's Hospital · USAbbott (United States) · USUniversity of Illinois Urbana-Champaign · USBeth Israel Deaconess Medical Center · US

Funding

Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI Hisashi Umemori · 2021 to 2026
$9.4M
Multi-site Data for Nutrition Studies in Healthy Early ChildhoodR03HD107124 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI OU, YANGMING · 2022 to 2023
$177k
NICHD NIH HHS P50 HD105351NICHD NIH HHS R03 HD107124
6 · The paper itself

Abstract

Breastmilk provides key nutrients and bio-active factors that contribute to infant neurodevelopment. Optimizing maternal nutrition could provide further benefit to psychomotor outcomes. Our observational cohort pilot study aims to determine if breastfeeding extent and breastmilk nutrients correlate with psychomotor outcomes at school age. The breastfeeding proportion at 3 months of age and neurodevelopmental outcomes at 3-5 years of age were recorded for 33 typically developing newborns born after uncomplicated pregnancies. The association between categorical breastfeeding proportion and neurodevelopmental outcome scores was determined for the cohort using a Spearman correlation with and without the inclusion of parental factors. Vitamin E and carotenoid levels were determined in breastmilk samples from 14 of the mothers. After the inclusion of parental education and income as covariates, motor skill scores positively correlated with breastmilk contents of α-tocopherol (Spearman coefficient 0.88,

Indexed as

Breast FeedingLuteinalpha-TocopherolFemaleHumansInfantInfant, NewbornMotor SkillsPilot ProjectsPregnancyZeaxanthinsalpha-TocopherolLuteinZeaxanthinsbreastfeedingluteinmaternal nutritionneurodevelopmental outcomeszeaxanthinα-tocopherol

Identifiers

PMID35684014
PMCPMC9182886
OpenAlexW4281850687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.