Evidence map›Paper›PMID 35684000›Full record

ArticleNutrients2022

Guoxiang Shi, Yubi Lin, Yuanyuan Wu, Jing Zhou, Lixiang Cao, Jiyan Chen, Yong Li, Ning Tan, Shilong Zhong

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Guoxiang ShiGuangdong Provincial Key Laboratory of Coronary, Department of Pharmacy, Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou 510080, China.
Yubi LinGuangdong Provincial Key Laboratory of Coronary, Department of Pharmacy, Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou 510080, China.
Yuanyuan WuGuangdong Provincial Key Laboratory of Coronary, Department of Pharmacy, Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou 510080, China.
Jing ZhouGuangdong Provincial Key Laboratory of Coronary, Department of Pharmacy, Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou 510080, China.
Lixiang CaoSchool of Medicine, Sun Yat-sen University, Guangzhou 510317, China.
Jiyan ChenGuangdong Provincial Key Laboratory of Coronary, Department of Pharmacy, Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou 510080, China.
Yong LiDepartment of Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510317, China.
Ning TanGuangdong Provincial Key Laboratory of Coronary, Department of Pharmacy, Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou 510080, China.
Shilong ZhongGuangdong Provincial Key Laboratory of Coronary, Department of Pharmacy, Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou 510080, China.
Guangdong Provincial People's Hospital · CNGuangdong Academy of Medical Sciences · CNGuangdong Medical College · CNSouth China University of Technology · CNSun Yat-sen University · CN

Funding

Science and Technology Development Projects of Guangdong Province, China No. 2017B0303314041Science and Technology Planning Project of Guangdong Province of China No. 2019A050510025the Key research and development program of Guangdong Province, China No. 2019B020229003
6 · The paper itself

Abstract

backgroundThe gut microbial ecosystem is an important factor that regulates host health and the onset of chronic diseases, such as inflammatory bowel diseases, obesity, hyperlipidemia, and diabetes mellitus, which are important risk factors for atherosclerosis. However, the links among diet, microbiota composition, and atherosclerotic progression are unclear. METHODS AND

resultsFour-week-old mice (

conclusionsgut microbiota dysbiosis was induced by BFS. It was characterized by reduced LAC and increased DSV abundance and led to the deterioration of glucose/lipid metabolic dysfunction and inflammatory response, which likely promoted aorta plaque formation and the progression of atherosclerosis.

Indexed as

Aortic DiseasesAtherosclerosisGastrointestinal MicrobiomeAnimalsAortaBacteroides fragilisDietary SupplementsDiet, High-FatDisease Models, AnimalDysbiosisEcosystemInflammationMiceMice, Inbred C57BLatheroscleroticdysbiosisgut microbiotametabolic syndrome

Identifiers

PMID35684000
PMCPMC9183096
OpenAlexW4281481044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.