Graphene Quantum Dots and Phthalocyanines Turn-OFF-ON Photoluminescence Nanosensor for ds-DNA.

Ana M Santiago, Carla I M Santos, Leandro M O Lourenço, Inês F A Mariz, João P C Tomé, Ermelinda Maçôas

Abstract read

In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Interaction of Carbon Dots with Nucleic Acids Is Driven by Their Surface Charge.Journal of chemical information and modeling · 2026
Article

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ana M SantiagoCentro de Química Estrutural, Institute of Molecular Science and Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.

Carla I M SantosCentro de Química Estrutural, Institute of Molecular Science and Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.

Leandro M O LourençoLAQV-REQUIMTE and Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-1624-6825

Inês F A MarizCentro de Química Estrutural, Institute of Molecular Science and Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.

João P C ToméCentro de Química Estrutural, Institute of Molecular Science and Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.

Ermelinda MaçôasCentro de Química Estrutural, Institute of Molecular Science and Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.ORCID 0000-0001-8506-7025

Funding

Fundação para a Ciência e Tecnologia UIDB/00100/2020, LA/P/0056/2020, UIDB/50006/2020, P2020-PTDC/QUI-QOR/31770/2017, LISBOA-01-0145-FEDER-029319, PTDC/NAN-MAT/29317/2017, 2020.01763.CEECIND

6 · The paper itself

Abstract

Supramolecular hybrids of graphene quantum dots (GQDs) and phthalocyanine (Pc) dyes were studied as turn-OFF-ON photoluminescence nanosensors for detection of ds-DNA. Pcs with four (Pc4) and eight (Pc8) positive charges were selected to interact with negatively charged GQDs. The photoluminescence of the GQDs was quenched upon interaction with the Pcs, due to the formation of non-emissive complexes. In the presence of ds-DNA, the Pcs interacted preferentially with the negatively charged ds-DNA, lifting the quenching effect over the photoluminescence of the GQDs and restoring their emission intensity. The best performance as a sensor of ds-DNA was registered for the GQD-Pc8, with a limit of detection (LOD) in the picomolar range. The LOD for GQD-Pc8 was more than one order of magnitude lower and its sensitivity was about a factor of three higher than that of the analogue GQD-Pc4 nanosensor. The sensitivity and selectivity of this simple GQD-Pc8 nanosensor is comparable to those of the more sophisticated carbon-based nanosensors for DNA reported previously.

Indexed as

DNAgraphene quantum dotphotoluminescencephthalocyaninesensor

Identifiers

PMID35683746

DOI10.3390/nano12111892

PMCPMC9182175

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.