Evidence map›Paper›PMID 35683685›Full record

ReviewNanomaterials (Basel, Switzerland)2022

Advances in Electrospun Hybrid Nanofibers for Biomedical Applications.

Viraj P Nirwan, Tomasz Kowalczyk, Julia Bar, Matej Buzgo, Eva Filová, Amir Fahmi

Open access · goldAbstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Chitosan/PEO Nanofibers as a Delivery Platform for Sustained Release ofInternational journal of molecular sciences · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Viraj P NirwanFaculty of Technology and Bionics, Rhine-Waal University of Applied Science, Marie-Curie-Straβe 1, 47533 Kleve, Germany.ORCID 0000-0002-3726-7783
Tomasz KowalczykInstitute of Fundamental Technological Research, Polish Academy of Sciences (IPPT PAN), Pawinskiego 5B, 02-106 Warsaw, Poland.ORCID 0000-0003-2381-4122
Julia BarDepartment of Immunopathology and Molecular Biology, Medical University, Bujwida 44, 50-345 Wroclaw, Poland.
Matej BuzgoBIOFABICS, Rua Alfredo Allen 455, 4200-135 Porto, Portugal.
Eva FilováDepartment of Tissue Engineering, Institute of Experimental Medicine of the Czceh Academy of Sciences, Vídeňská 1083, 14220 Prague, Czech Republic.ORCID 0000-0003-1028-605X
Amir FahmiFaculty of Technology and Bionics, Rhine-Waal University of Applied Science, Marie-Curie-Straβe 1, 47533 Kleve, Germany.ORCID 0000-0003-3784-1324
Rhine-Waal University of Applied Sciences · DECzech Academy of Sciences, Institute of Experimental Medicine · CZInstitute of Fundamental Technological Research · PLWroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrospun hybrid nanofibers, based on functional agents immobilized in polymeric matrix, possess a unique combination of collective properties. These are beneficial for a wide range of applications, which include theranostics, filtration, catalysis, and tissue engineering, among others. The combination of functional agents in a nanofiber matrix offer accessibility to multifunctional nanocompartments with significantly improved mechanical, electrical, and chemical properties, along with better biocompatibility and biodegradability. This review summarizes recent work performed for the fabrication, characterization, and optimization of different hybrid nanofibers containing varieties of functional agents, such as laser ablated inorganic nanoparticles (NPs), which include, for instance, gold nanoparticles (Au NPs) and titanium nitride nanoparticles (TiNPs), perovskites, drugs, growth factors, and smart, inorganic polymers. Biocompatible and biodegradable polymers such as chitosan, cellulose, and polycaprolactone are very promising macromolecules as a nanofiber matrix for immobilizing such functional agents. The assimilation of such polymeric matrices with functional agents that possess wide varieties of characteristics require a modified approach towards electrospinning techniques such as coelectrospinning and template spinning. Additional focus within this review is devoted to the state of the art for the implementations of these approaches as viable options for the achievement of multifunctional hybrid nanofibers. Finally, recent advances and challenges, in particular, mass fabrication and prospects of hybrid nanofibers for tissue engineering and biomedical applications have been summarized.

Indexed as

bone regenerationdrug deliveryelectrospinningfunctional agentshybrid nanofibersnanomedicinenanoparticlestissue engineering

Identifiers

PMID35683685
PMCPMC9181850
OpenAlexW4281891646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.