Evidence map›Paper›PMID 35683504›Full record

ArticleJournal of clinical medicine2022

Heart Failure with Reduced Ejection Fraction and Prognostic Scales: The Impact of Exercise Modality in Cardiopulmonary Exercise Tests.

Julia Herrero Huertas, Marta García Clemente, Beatriz Díaz Molina, José Luis Lambert Rodríguez, Marta Íscar Urrutia

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Cardiopulmonary Test in Fontan Patients: Is the Type of Ergometer Critical?Journal of cardiovascular development and disease · 2025
    Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Julia Herrero HuertasDepartment of Pneumology, Fundación Jiménez Díaz University Hospital, 28040 Madrid, Spain.ORCID 0000-0002-8635-3688
Marta García ClementeDepartment of Pneumology, Asturias Central University Hospital, 33011 Oviedo, Spain.ORCID 0000-0003-0463-5946
Beatriz Díaz MolinaDepartment of Cardiology, Asturias Central University Hospital, 33011 Oviedo, Spain.ORCID 0000-0002-7773-8121
José Luis Lambert RodríguezDepartment of Cardiology, Asturias Central University Hospital, 33011 Oviedo, Spain.ORCID 0000-0002-7507-2127
Marta Íscar UrrutiaDepartment of Pneumology, Asturias Central University Hospital, 33011 Oviedo, Spain.ORCID 0000-0003-3470-7664
Hospital Universitario Central de Asturias · ESHospital Universitario Fundación Jiménez Díaz · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cardiopulmonary exercise (CPET) test is an essential tool to determine the severity, prognosis, and need for invasive treatments in heart failure with reduced ejection fraction (HFrEF) but disregards the exercise modality. The present study aimed at analyzing the differences between treadmill and cycle-ergometer exercises. This was a prospective study, involving 65 patients with HfrEF who performed treadmill exercise followed by cycle-ergometer exercise 72 h later. We enrolled 65 patients, aged 58 ± 9 years, with an ejection fraction of 29 ± 9%. Peak VO2 was 20% greater (95% CI: 18−21%; p < 0.000) on the treadmill, and the ventilatory efficiency estimated by the VE/VCO2 slope (32 ± 8 vs. 34 ± 9; p < 0.05). The ventilatory response was greater on the treadmill: maximum ventilation (55 ± 16 vs. 46 ± 11 L/min; p < 0.000) and ventilatory reserve at the maximum effort (28 ± 17 vs. 41 ± 15%; p < 0.000). These values led to a change in the functional class of 23 (51%) patients and ventilatory class of 28 (47%) patients. Differences in the main parameters, including peak VO2 and VE/VCO2, impact prognostic scales and possible advanced treatments; therefore, the results should be interpreted in accordance with the exercise modality.

Indexed as

cardiopulmonary exercise testscycle ergometerheart failure with reduced ejection fractionprognostic scalestreadmillVE/VCO2 slopeVO2

Identifiers

PMID35683504
PMCPMC9181537
OpenAlexW4281634439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.