Evidence map›Paper›PMID 35683496›Full record

ArticleJournal of clinical medicine2022

Exploring Retinal Blood Vessel Diameters as Biomarkers in Multiple Sclerosis.

Dragana Drobnjak Nes, Pål Berg-Hansen, Sigrid A de Rodez Benavent, Einar A Høgestøl, Mona K Beyer, Daniel A Rinker, Nina Veiby, Mia Karabeg, Beáta Éva Petrovski, Elisabeth G Celius and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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  6. Editorial: Imaging in Ophthalmology.Journal of clinical medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Dragana Drobnjak NesCenter of Eye Research, Department of Ophthalmology, Oslo University Hospital, 0450 Oslo, Norway.
Pål Berg-HansenDepartment of Neurology, Oslo University Hospital, 0372 Oslo, Norway.
Sigrid A de Rodez BenaventCenter of Eye Research, Department of Ophthalmology, Oslo University Hospital, 0450 Oslo, Norway.
Einar A HøgestølDepartment of Neurology, Oslo University Hospital, 0372 Oslo, Norway.ORCID 0000-0001-8446-2111
Mona K BeyerInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0372 Oslo, Norway.
Daniel A RinkerDepartment of Neurology, Oslo University Hospital, 0372 Oslo, Norway.
Nina VeibyCenter of Eye Research, Department of Ophthalmology, Oslo University Hospital, 0450 Oslo, Norway.ORCID 0000-0002-6743-5282
Mia KarabegCenter of Eye Research, Department of Ophthalmology, Oslo University Hospital, 0450 Oslo, Norway.
Beáta Éva PetrovskiInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0372 Oslo, Norway.
Elisabeth G CeliusDepartment of Neurology, Oslo University Hospital, 0372 Oslo, Norway.ORCID 0000-0002-9127-6488
Hanne F HarboDepartment of Neurology, Oslo University Hospital, 0372 Oslo, Norway.
Goran PetrovskiCenter of Eye Research, Department of Ophthalmology, Oslo University Hospital, 0450 Oslo, Norway.ORCID 0000-0003-2905-9252
Oslo University Hospital · NOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to determine whether retinal vessel diameters and retinal oxygen saturation in newly diagnosed patients with multiple sclerosis (pwMS) are different from those of a healthy population. Retinal blood vessel diameters were measured using imaging with a spectrophotometric non-invasive retinal oximeter. Twenty-three newly diagnosed untreated relapsing-remitting MS (RRMS) patients (mean age: 32.2 ± 7.5 years, age range = 18-50 years, 56.5% female) were measured and compared to 23 age- and sex-matched healthy controls (HCs) (mean age: 34.8 ± 8.1 years). Patients with Optic Neuritis were excluded. Retinal venular diameter (143.8 µm versus 157.8 µm: mean;

Indexed as

fundus imagingmultiple sclerosisretinal oximetryretinal vessel diameter

Identifiers

PMID35683496
PMCPMC9181486
OpenAlexW4281684101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.