Evidence map›Paper›PMID 35683481›Full record

ArticleJournal of clinical medicine2022

Genomic Relevance of

Walizeb Khan, Washaakh Ahmad, Anwar M Hashem, Shadi Zakai, Shafiul Haque, Muhammad Faraz Arshad Malik, Steve Harakeh, Farhan Haq

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Walizeb KhanDepartment of Biosciences, COMSATS University, Islamabad 44000, Pakistan.ORCID 0000-0002-1760-3516
Washaakh AhmadDepartment of Biosciences, COMSATS University, Islamabad 44000, Pakistan.
Anwar M HashemDepartment of Medical Microbiology and Parasitology, Faculty of Medicine, King Abdulaziz University, Jeddah 22252, Saudi Arabia.ORCID 0000-0002-8471-7011
Shadi ZakaiDepartment of Medical Microbiology and Parasitology, Faculty of Medicine, King Abdulaziz University, Jeddah 22252, Saudi Arabia.ORCID 0000-0003-3261-304X
Shafiul HaqueResearch and Scientific Studies Unit, College of Nursing and Allied Health Sciences, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0002-2989-121X
Muhammad Faraz Arshad MalikDepartment of Biosciences, COMSATS University, Islamabad 44000, Pakistan.ORCID 0000-0002-2230-0990
Steve HarakehKing Fahd Medical Research Center, King Abdulaziz University, Jeddah 22230, Saudi Arabia.ORCID 0000-0001-7512-8787
Farhan HaqDepartment of Biosciences, COMSATS University, Islamabad 44000, Pakistan.ORCID 0000-0001-9190-4360
COMSATS University Islamabad · PKKing Abdulaziz University · SAJazan University · SA

Funding

Higher Education Commission NRPU 7036
6 · The paper itself

Abstract

The Fibroblast Growth Factor Receptors (FGFRs) are known to regulate cancer metabolism in different tumor types, including hepatocellular carcinoma (HCC). Several risk factors are associated with HCC, of which viral infections (Hepatitis B and C) and cirrhosis are prominent. In Pakistan as well as in highly developed countries like the United States, hepatitis C virus HCV infections are most commonly reported in HCC. Here, we aimed to investigate the clinical relevance of FGFR receptors in HCC and their role in HCV-positive HCC cases. 264 HCC samples along with their clinical information and 96 normal liver samples were collected. qPCR was done to estimate the expression of

Indexed as

cirrhosisFGFR2HCCHCV+HCV-induced HCC

Identifiers

PMID35683481
PMCPMC9181427
OpenAlexW4281765040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.