Evidence map›Paper›PMID 35683451›Full record

ArticleJournal of clinical medicine2022

Risk Factors for Mortality in Cardiac Implantable Electronic Device (CIED) Infections: A Systematic Review and Meta-Analysis.

Jinghao Nicholas Ngiam, Tze Sian Liong, Meng Ying Sim, Nicholas W S Chew, Ching-Hui Sia, Siew Pang Chan, Toon Wei Lim, Tiong-Cheng Yeo, Paul Anantharajah Tambyah, Poay Huan Loh and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Clinical impact of capsulectomy during cardiac implantable electronic device generator replacement: a prospective randomized trial.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Trial
  2. Article
  3. Review
  4. Clinical characteristics, treatment, and outcomes in CIED-related vs. left-sided infective endocarditis: a nationwide study from the NIDUS registry.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  5. Review
  6. Infective endocarditis: it takes a team.European heart journal · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Jinghao Nicholas NgiamDivision of Infectious Diseases, Department of Medicine, National University Health System, Singapore 119228, Singapore.ORCID 0000-0002-3339-7281
Tze Sian LiongDepartment of Medicine, National University Health System, Singapore 119228, Singapore.
Meng Ying SimDepartment of Medicine, National University Health System, Singapore 119228, Singapore.
Nicholas W S ChewDepartment of Cardiology, National University Heart Centre Singapore, National University Health System, Singapore 119074, Singapore.ORCID 0000-0002-0640-0430
Ching-Hui SiaDepartment of Cardiology, National University Heart Centre Singapore, National University Health System, Singapore 119074, Singapore.ORCID 0000-0002-2764-2869
Siew Pang ChanYong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Toon Wei LimDepartment of Cardiology, National University Heart Centre Singapore, National University Health System, Singapore 119074, Singapore.ORCID 0000-0002-3429-9237
Tiong-Cheng YeoDepartment of Cardiology, National University Heart Centre Singapore, National University Health System, Singapore 119074, Singapore.
Paul Anantharajah TambyahDivision of Infectious Diseases, Department of Medicine, National University Health System, Singapore 119228, Singapore.
Poay Huan LohDepartment of Cardiology, National University Heart Centre Singapore, National University Health System, Singapore 119074, Singapore.
Kian Keong PohDepartment of Cardiology, National University Heart Centre Singapore, National University Health System, Singapore 119074, Singapore.ORCID 0000-0003-3515-7924
William K F KongDepartment of Cardiology, National University Heart Centre Singapore, National University Health System, Singapore 119074, Singapore.
National University of Singapore · SGNational University Health System · SGNational University Heart Centre Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfections following cardiac implantable electronic device (CIED) implantation can require surgical device removal and often results in significant cost, morbidity, and potentially mortality. We aimed to systemically review the literature and identify risk factors associated with mortality following CIED infection.

methodsElectronic searches (up to June 2021) were performed on PubMed and Scopus. Twelve studies (10 retrospective, 2 prospective cohort studies) were included for analysis. Meta-analysis was conducted with the restricted maximum likelihood method, with mortality as the outcome. The overall mortality was 13.7% (438/1398) following CIED infection.

resultsOn meta-analysis, the male sex (OR 0.77, 95%CI 0.57-1.01, I

conclusionWe identified important risk factors associated with mortality in CIED infections, including

Indexed as

cardiac implantable electronic deviceinfectionmortalityoutcomes

Identifiers

PMID35683451
PMCPMC9181812
OpenAlexW4281661141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.