Evidence map›Paper›PMID 35683431›Full record

ArticleJournal of clinical medicine2022

Triglyceride and Glucose Index as a Screening Tool for Nonalcoholic Liver Disease in Patients with Metabolic Syndrome.

Anca Maria Amzolini, Mircea-Cătălin Forțofoiu, Anca Barău Alhija, Ionela Mihaela Vladu, Diana Clenciu, Adina Mitrea, Maria Forțofoiu, Daniela Matei, Magdalena Diaconu, Marinela Sinziana Tudor and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Metabolic Syndrome and Insulin Resistance in Romania.International journal of molecular sciences · 2025
    Article
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  12. Review
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  14. Article
  15. The burden of cancer in metabolic dysfunction-associated steatotic liver disease.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Anca Maria AmzoliniDepartment of Medical Semiology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Mircea-Cătălin ForțofoiuDepartment of Medical Semiology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0002-3341-1442
Anca Barău AlhijaDepartment of Medical Semiology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Ionela Mihaela VladuDepartment of Diabetes, Nutrition and Metabolic Diseases, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Diana ClenciuDepartment of Diabetes, Nutrition and Metabolic Diseases, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Adina MitreaDepartment of Diabetes, Nutrition and Metabolic Diseases, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0002-5310-3033
Maria ForțofoiuDepartment of Internal Medicine 2, "Philanthropy" Clinical Municipal Hospital of Craiova, 200143 Craiova, Romania.ORCID 0000-0002-2056-6779
Daniela MateiDepartment of Physiotherapy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Magdalena DiaconuDepartment of Pharmacology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Marinela Sinziana TudorDoctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Elena Simona MicuDepartment of Medical Semiology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
University of Medicine and Pharmacy of Craiova · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNonalcoholic fatty liver disease (NAFLD) is regarded as a component of metabolic syndrome, which involves insulin resistance (IR) as the primary physiopathological event. The aim of this study was to establish the association between IR, assessed using the triglyceride and glucose index (TyG), and histopathological features of NAFLD lesions.

methodsThe study included 113 patients with metabolic syndrome. Fasting plasma glucose (FPG), fasting lipid profiles and liver enzymes were measured. IR was assessed by the TyG index. Liver biopsy was performed for assessment steatosis and fibrosis.

resultsthe TyG index had a mean value of 8.93 ± 1.45, with a higher value in the patients with overweight (

conclusionthe TyG index is a facile tool that can be used to identify individuals at risk for NAFLD.

Indexed as

liver biopsymetabolic syndromenonalcoholic liver diseaseobesitytriglyceride and glucose index

Identifiers

PMID35683431
PMCPMC9181222
OpenAlexW4281800991

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.