Evidence map›Paper›PMID 35683397›Full record

ReviewJournal of clinical medicine2022

Antithrombotic Therapy in Elderly Patients with Acute Coronary Syndromes.

Clara Bonanad, Francisca Esteve-Claramunt, Sergio García-Blas, Ana Ayesta, Pablo Díez-Villanueva, Jose-Ángel Pérez-Rivera, José Luis Ferreiro, Joaquim Cánoves, Francisco López-Fornás, Albert Ariza Solé and 13 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Clara BonanadCardiology Department, Clinic University Hospital of Valencia, 46010 Valencia, Spain.ORCID 0000-0001-8665-7107
Francisca Esteve-ClaramuntDepartment of Nursing, Faculty of Health Sciences, European University of Valencia, 46010 Valencia, Spain.ORCID 0000-0002-4539-8003
Sergio García-BlasCardiology Department, Clinic University Hospital of Valencia, 46010 Valencia, Spain.ORCID 0000-0002-1998-3735
Ana AyestaCardiology Department, Central University Hospital of Asturias, 33011 Oviedo, Spain.
Pablo Díez-VillanuevaCardiology Department, La Princesa University Hospital, 28006 Madrid, Spain.
Jose-Ángel Pérez-RiveraCardiology Department, University Hospital of Burgos, Isabel I University, 09003 Burgos, Spain.ORCID 0000-0003-1451-1445
José Luis FerreiroCentro de Investigación Biomédica en Red Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain.ORCID 0000-0003-1202-9575
Joaquim CánovesCardiology Department, Clinic University Hospital of Valencia, 46010 Valencia, Spain.
Francisco López-FornásCardiology Department, Clinic University Hospital of Valencia, 46010 Valencia, Spain.
Albert Ariza SoléCardiology Department, University Hospital of Burgos, Isabel I University, 09003 Burgos, Spain.ORCID 0000-0002-0819-6656
Sergio RaposeriasCardiology Department, Álvaro Cunqueiro University Hospital, 36213 Vigo, Spain.
David VivasDepartment of Medicine, Cardiovascular Institute, San Carlos University Hospital, Complutense University, 28040 Madrid, Spain.
Regina BlancoCardiology Department, Quirónsalud Hospital of Valencia, 46010 Valencia, Spain.
Daznia Bompart BerroteránDepartment of Medicine, University of Valencia, 46010 Valencia, Spain.ORCID 0000-0003-0117-2085
Alberto CorderoCentro de Investigación Biomédica en Red Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain.ORCID 0000-0003-0000-7109
Julio NúñezCardiology Department, Clinic University Hospital of Valencia, 46010 Valencia, Spain.ORCID 0000-0003-1672-7119
Lorenzo FácilaCardiology Department, General University Hospital of Valencia, 46014 Valencia, Spain.ORCID 0000-0003-1402-4364
Iván J Núñez-GilDepartment of Medicine, Cardiovascular Institute, San Carlos University Hospital, Complutense University, 28040 Madrid, Spain.
José Luis GórrizINCLIVA Biomedical Research Institute, 46010 Valencia, Spain.ORCID 0000-0002-1134-9051
Vicente BodíCardiology Department, Clinic University Hospital of Valencia, 46010 Valencia, Spain.
Manuel Martínez-SellesCardiology Department, Hospital Universitario Gregorio Marañón, Universidad Europea, Complutense University, 28040 Madrid, Spain.ORCID 0000-0003-0289-6229
Juan Miguel Ruiz NodarServicio de Cardiología, Hospital General Universitario de Alicante, Instituto de Investigación Sanitaria y Biomédica de Alicante ISABIAL, CIBER-CV, 03010 Alicante, Spain.ORCID 0000-0002-8480-0835
Francisco Javier ChorroCardiology Department, Clinic University Hospital of Valencia, 46010 Valencia, Spain.

Funding

Generalitat Valenciana PROMETEO/21/008Instituto de Salud Carlos III CIBERCV16/11/00486Instituto de Salud Carlos III JR/21/00041Instituto de Salud Carlos III PI20/00637
6 · The paper itself

Abstract

The treatment of acute coronary syndrome (ACS) in elderly patients continues to be a challenge because of the characteS.G.B.ristics of this population and the lack of data and specific recommendations. This review summarizes the current evidence about critical points of oral antithrombotic therapy in elderly patients. To this end, we discuss the peculiarities and differences reported referring to dual antiplatelet therapy (DAPT) in ACS management in elderly patients and what might be the best option considering these population characteristics. Furthermore, we analyze antithrombotic strategies in patients with atrial fibrillation (AF), with a particular focus on those cases that also present coronary artery disease (CAD). It is imperative to deepen our knowledge regarding the management of these challenging patients through real-world data and specifically designed geriatric studies to help resolve the questions remaining in their disease management.

Indexed as

acute coronary syndromeantiplatelet therapyclopidogrelelderlyprasugrelticagrelor

Identifiers

PMID35683397
PMCPMC9181473

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.