Evidence map›Paper›PMID 35683392›Full record

ArticleJournal of clinical medicine2022

The Role of Lung Ultrasound Monitoring in Early Detection of Ventilator-Associated Pneumonia in COVID-19 Patients: A Retrospective Observational Study.

Silvia Mongodi, Nello De Vita, Giulia Salve, Silvia Bonaiti, Francesco Daverio, Margherita Cavagnino, Gilda Siano, Alessandro Amatu, Giuseppe Maggio, Valeria Musella and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Observational
  7. Article
  8. Review
  9. Thoracic UltrasONOgraphy Reporting: The TUONO Consensus.Diagnostics (Basel, Switzerland) · 2023
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Silvia MongodiAnesthesia and Intensive Care, Fondazione IRCCS Policlinico San Matteo, DEA piano-1, Viale Camillo Golgi, 19, 27100 Pavia, Italy.ORCID 0000-0002-1987-8599
Nello De VitaAnesthesia and Intensive Care, Fondazione IRCCS Policlinico San Matteo, DEA piano-1, Viale Camillo Golgi, 19, 27100 Pavia, Italy.ORCID 0000-0003-3218-8653
Giulia SalveUnit of Anaesthesia and Intensive Care, Department of Clinical-Surgical, Diagnostic, and Paediatric Sciences, Università di Pavia, Viale Brambilla, 74, 27100 Pavia, Italy.
Silvia BonaitiAnesthesia and Intensive Care, Fondazione IRCCS Policlinico San Matteo, DEA piano-1, Viale Camillo Golgi, 19, 27100 Pavia, Italy.
Francesco DaverioUnit of Anaesthesia and Intensive Care, Department of Clinical-Surgical, Diagnostic, and Paediatric Sciences, Università di Pavia, Viale Brambilla, 74, 27100 Pavia, Italy.
Margherita CavagninoUnit of Anaesthesia and Intensive Care, Department of Clinical-Surgical, Diagnostic, and Paediatric Sciences, Università di Pavia, Viale Brambilla, 74, 27100 Pavia, Italy.
Gilda SianoUnit of Anaesthesia and Intensive Care, Department of Clinical-Surgical, Diagnostic, and Paediatric Sciences, Università di Pavia, Viale Brambilla, 74, 27100 Pavia, Italy.
Alessandro AmatuAnesthesia and Intensive Care, Fondazione IRCCS Policlinico San Matteo, DEA piano-1, Viale Camillo Golgi, 19, 27100 Pavia, Italy.ORCID 0000-0003-4063-9493
Giuseppe MaggioAnesthesia and Intensive Care, Fondazione IRCCS Policlinico San Matteo, DEA piano-1, Viale Camillo Golgi, 19, 27100 Pavia, Italy.
Valeria MusellaClinical Epidemiology and Biometrics, Fondazione IRCCS Policlinico S. Matteo, Viale Camillo Golgi, 19, 27100 Pavia, Italy.
Catherine KlersyClinical Epidemiology and Biometrics, Fondazione IRCCS Policlinico S. Matteo, Viale Camillo Golgi, 19, 27100 Pavia, Italy.
Rosanna VaschettoDepartment of Translational Medicine, Università del Piemonte Orientale, Via Solaroli, 17, 28100 Novara, Italy.ORCID 0000-0003-4625-4367
Belaid BouhemadDepartment of Anaesthesiology and Intensive Care, C.H.U. Dijon, BP 77908, CEDEX, 21709 Dijon, France.
Francesco MojoliAnesthesia and Intensive Care, Fondazione IRCCS Policlinico San Matteo, DEA piano-1, Viale Camillo Golgi, 19, 27100 Pavia, Italy.
Policlinico San Matteo Fondazione · ITUniversity of Pavia · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITUniversité Bourgogne Franche-Comté · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Specific lung ultrasound signs combined with clinical parameters allow for early diagnosis of ventilator-associated pneumonia in the general ICU population. This retrospective cohort study aimed to determine the accuracy of lung ultrasound monitoring for ventilator-associated pneumonia diagnosis in COVID-19 patients. Clinical (i.e., clinical pulmonary infection score) and ultrasound (i.e., presence of consolidation and a dynamic linear−arborescent air bronchogram, lung ultrasound score, ventilator-associated lung ultrasound score) data were collected on the day of the microbiological sample (pneumonia-day) and 48 h before (baseline) on 55 bronchoalveolar lavages of 33 mechanically-ventilated COVID-19 patients who were monitored daily with lung ultrasounds. A total of 26 samples in 23 patients were positive for ventilator-associated pneumonia (pneumonia cases). The onset of a dynamic linear−arborescent air bronchogram was 100% specific for ventilator-associated pneumonia. The ventilator-associated lung ultrasound score was higher in pneumonia-cases (2.5 (IQR 1.0 to 4.0) vs. 1.0 (IQR 1.0 to 1.0); p < 0.001); the lung ultrasound score increased from baseline in pneumonia-cases only (3.5 (IQR 2.0 to 6.0) vs. −1.0 (IQR −2.0 to 1.0); p = 0.0001). The area under the curve for clinical parameters, ventilator-associated pneumonia lung ultrasound score, and lung ultrasound score variations were 0.472, 0.716, and 0.800, respectively. A newly appeared dynamic linear−arborescent air bronchogram is highly specific for ventilator-associated pneumonia in COVID-19 patients. A high ventilator-associated pneumonia lung ultrasound score (or an increase in the lung ultrasound score) orients to ventilator-associated pneumonia.

Indexed as

aeration monitoringaeration quantificationarborescent air bronchogramlung monitoringlung ultrasoundlung ultrasound scorenosocomial infectionventilator-associated pneumonia

Identifiers

PMID35683392
PMCPMC9181291
OpenAlexW4281711384

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.