Evidence map›Paper›PMID 35683386›Full record

ArticleJournal of clinical medicine2022

General Anesthesia-Related Drop in Diastolic Blood Pressure May Impact the Long-Term Outcome in Stroke Patients Undergoing Thrombectomy.

Alan Abada, Peter Csecsei, Erzsebet Ezer, Gabor Lenzser, Peter Hegyi, Alex Szolics, Akos Merei, Andrea Szentesi, Tihamer Molnar

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alan AbadaDepartment of Anesthesiology and Intensive Care, Medical School, University of Pecs, 7624 Pecs, Hungary.
Peter CsecseiDepartment of Neurosurgery, Medical School, University of Pecs, 7624 Pecs, Hungary.ORCID 0000-0002-4982-2481
Erzsebet EzerDepartment of Anesthesiology and Intensive Care, Medical School, University of Pecs, 7624 Pecs, Hungary.
Gabor LenzserDepartment of Neurosurgery, Medical School, University of Pecs, 7624 Pecs, Hungary.
Peter HegyiCentre for Translational Medicine, Semmelweiss University, 1085 Budapest, Hungary.
Alex SzolicsDepartment of Radiology, Örebro University Hospital, 70281 Örebro, Sweden.
Akos MereiDepartment of Anesthesiology and Intensive Care, Medical School, University of Pecs, 7624 Pecs, Hungary.
Andrea SzentesiCentre for Translational Medicine, Semmelweiss University, 1085 Budapest, Hungary.
Tihamer MolnarDepartment of Anesthesiology and Intensive Care, Medical School, University of Pecs, 7624 Pecs, Hungary.ORCID 0000-0002-6149-9787

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Several factors affect the efficacy of endovascular thrombectomy (EVT); however, the anesthesia-related factors have not been fully explored. We aimed to identify independent predictors of outcome by analyzing procedural factors based on a multicentric stroke registry. Methods: Data of consecutive patients with acute ischemic stroke (AIS) were extracted from the prospective STAY ALIVE stroke registry. Demographic, clinical, and periprocedural factors including hemodynamic values were analyzed in patients undergoing thrombectomy with either general anesthesia (GA) or conscious sedation (CS). Independent predictors of outcome both at 30 and 90 days based on the modified Rankin Scale (mRS: 0−2 as favorable outcome) were also explored. Results: A total of 199 patients (GA: 76 (38%) vs. CS: 117 (59%); in addition, six patients were converted from CS to GA) were included. The minimum value of systolic, diastolic, and mean arterial pressure was significantly lower in the GA compared to the CS group, and GA was associated with a longer onset to EVT time and a higher drop in all hemodynamic variables (all, p < 0.001). A higher drop in diastolic blood pressure (DBP) was even independently associated with a poor 90-day outcome (p = 0.024). Conclusion: A GA-related drop in DBP may independently predict a poor long-term outcome in stroke patients undergoing thrombectomy.

Indexed as

anesthesiablood pressureendovascular treatmentischemic strokeoutcome

Identifiers

PMID35683386
PMCPMC9181773

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.