Evidence map›Paper›PMID 35683373›Full record

ArticleJournal of clinical medicine2022

High-Throughput Sequencing of Complementarity Determining Region 3 in the Heavy Chain of B-Cell Receptor in Renal Transplant Recipients: A Preliminary Report.

Tsai-Hung Wu, Hsien-Tzung Liao, Tzu-Hao Li, Hung-Cheng Tsai, Niang-Cheng Lin, Cheng-Yen Chen, Shih-Feng Tsai, Tzu-Hao Huang, Chang-Youh Tsai, Chia-Li Yu

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Tsai-Hung WuDivision of Nephrology, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Hsien-Tzung LiaoDivision of Allergy, Immunology & Rheumatology, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Tzu-Hao LiDivision of Immunology & Rheumatology, Shin Kong Wu Ho Su Memorial Hospital, Taipei 11101, Taiwan.
Hung-Cheng TsaiDivision of Allergy, Immunology & Rheumatology, Taipei Veterans General Hospital, Taipei 11217, Taiwan.ORCID 0000-0002-0429-2608
Niang-Cheng LinDivision of Transplantation Surgery, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Cheng-Yen ChenDivision of Transplantation Surgery, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Shih-Feng TsaiInstitute of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan 35053, Taiwan.
Tzu-Hao HuangDepartment of Urology, Taipei Veterans General Hospital, Taipei 11217, Taiwan.ORCID 0000-0003-4847-9295
Chang-Youh TsaiDivision of Allergy, Immunology & Rheumatology, Fu Jen Catholic University Hospital, New Taipei City 24352, Taiwan.ORCID 0000-0002-4154-4018
Chia-Li YuDepartment of Internal Medicine, National Taiwan University Hospital, Taipei 100225, Taiwan.
Taipei Veterans General Hospital · TWChang Gung Memorial Hospital · TWFu Jen Catholic University · TWNational Health Research Institutes · TWNational Taiwan University Hospital · TW

Funding

Ministry of Science & Technology, Taiwan MOST 107-2314-B-075 -051-MY3Taipei Veterans General Hospital V107D-037-4, V109C-041
6 · The paper itself

Abstract

backgroundGraft failure resulting from rejection or any other adverse event usually originates from an aberrant and/or exaggerated immune response and is often catastrophic in renal transplantation. So, it is essential to monitor patients' immune status for detecting a rejection/graft failure early on.

methodsWe monitored the sequence change of complementary determining region 3 (CDR3) in B-cell receptor (BCR) immunoglobulin heavy-chain (

resultsDatasets covering VDJ regions of

conclusionsClonal diversity in

Indexed as

B cellclonal diversitycomplementary determining region 3 (CDR3)immune repertoire (iR)next-generation sequencing (NGS)renal transplantation

Identifiers

PMID35683373
PMCPMC9181060
OpenAlexW4281478538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.