Evidence map›Paper›PMID 35683190›Full record

ReviewMaterials (Basel, Switzerland)2022

Nanotechnology in the Diagnostic and Therapy of Hepatocellular Carcinoma.

Florin Graur, Aida Puia, Emil Ioan Mois, Septimiu Moldovan, Alexandra Pusta, Cecilia Cristea, Simona Cavalu, Cosmin Puia, Nadim Al Hajjar

Abstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Nanotechnology for the Diagnosis and Treatment of Liver Cancer.International journal of nanomedicine · 2024
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Florin GraurDepartment of Surgery, University of Medicine and Pharmacy "Iuliu Hatieganu", 400012 Cluj-Napoca, Romania.ORCID 0000-0002-5887-3408
Aida PuiaDepartment of General Practitioner, University of Medicine and Pharmacy "Iuliu Hatieganu", 400347 Cluj-Napoca, Romania.
Emil Ioan MoisDepartment of Surgery, University of Medicine and Pharmacy "Iuliu Hatieganu", 400012 Cluj-Napoca, Romania.
Septimiu MoldovanRegional Institute of Gastroenterology and Hepatology "Octavian Fodor", 400394 Cluj-Napoca, Romania.
Alexandra PustaDepartment of Analytical Chemistry, University of Medicine and Pharmacy "Iuliu Hatieganu", 400347 Cluj-Napoca, Romania.ORCID 0000-0001-7789-6798
Cecilia CristeaDepartment of Analytical Chemistry, University of Medicine and Pharmacy "Iuliu Hatieganu", 400347 Cluj-Napoca, Romania.ORCID 0000-0002-4158-3324
Simona CavaluDepartment of Medical Biophysics, Faculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, Romania.ORCID 0000-0001-7810-8925
Cosmin PuiaDepartment of Surgery, University of Medicine and Pharmacy "Iuliu Hatieganu", 400012 Cluj-Napoca, Romania.
Nadim Al HajjarDepartment of Surgery, University of Medicine and Pharmacy "Iuliu Hatieganu", 400012 Cluj-Napoca, Romania.

Funding

Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii PN-III-P2-2.1-PED-2019-4375/397/2020
6 · The paper itself

Abstract

Hepatocellular carcinoma is the most common liver malignancy and is among the top five most common cancers. Despite the progress of surgery and chemotherapy, the results are often disappointing, in part due to chemoresistance. This type of tumor has special characteristics that allow the improvement of diagnostic and treatment techniques used in clinical practice, by combining nanotechnology. This article presents a brief review of the literature focused on nano-conditioned diagnostic methods, targeted therapy, and therapeutic implications for the pathology of hepatocellular carcinoma. Within each subdomain, several modern technologies with significant impact were highlighted: serological, imaging, or histopathological diagnosis; intraoperative detection; carrier-type nano-conditioned therapy, thermal ablation, and gene therapy. The prospects offered by nanomedicine will strengthen the hope of more efficient diagnoses and therapies in the future.

Indexed as

cancer diagnosishepatocellular carcinomananomedicinesmart therapytargeting

Identifiers

PMID35683190
PMCPMC9182427

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.