Evidence map›Paper›PMID 35683135›Full record

ArticleMaterials (Basel, Switzerland)2022

Silver Nanoparticles Inhibit Metastasis of 4T1 Tumor in Mice after Intragastric but Not Intravenous Administration.

Kamil Brzóska, Maria Wojewódzka, Małgorzata Szczygiel, Agnieszka Drzał, Martyna Sniegocka, Dominika Michalczyk-Wetula, Eva Biela, Martyna Elas, Małgorzata Kucińska, Hanna Piotrowska-Kempisty and 4 more

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Kamil BrzóskaCentre for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland.ORCID 0000-0001-7310-5100
Maria WojewódzkaCentre for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland.
Małgorzata SzczygielDepartment of Biophysics and Cancer Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.ORCID 0000-0002-9548-1868
Agnieszka DrzałDepartment of Biophysics and Cancer Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.
Martyna SniegockaDepartment of Biophysics and Cancer Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.ORCID 0000-0001-5389-6419
Dominika Michalczyk-WetulaDepartment of Biophysics and Cancer Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.
Eva BielaDepartment of Biophysics and Cancer Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.
Martyna ElasDepartment of Biophysics and Cancer Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.ORCID 0000-0001-6296-2844
Małgorzata KucińskaDepartment of Toxicology, Poznan University of Medical Sciences, Dojazd 30, 60-631 Poznań, Poland.ORCID 0000-0002-3606-3623
Hanna Piotrowska-KempistyDepartment of Toxicology, Poznan University of Medical Sciences, Dojazd 30, 60-631 Poznań, Poland.
Lucyna Kapka-SkrzypczakDepartment of Molecular Biology and Translational Research, Institute of Rural Health, Jaczewskiego 2, 20-090 Lublin, Poland.
Marek MuriasDepartment of Toxicology, Poznan University of Medical Sciences, Dojazd 30, 60-631 Poznań, Poland.ORCID 0000-0002-2903-4912
Krystyna UrbańskaDepartment of Biophysics and Cancer Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.
Marcin KruszewskiCentre for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland.ORCID 0000-0003-4554-8566
Jagiellonian University · PLInstytut Chemii i Techniki Jądrowej · PLPoznan University of Medical Sciences · PLInstytut Medycyny Wsi im. Witolda Chodźki · PL

Funding

National Science Center 2014/15/B/NZ7/01036Polish Ministry of Science and Higher Education Statutory funding to the Institute of Nuclear Chemistry and Technology
6 · The paper itself

Abstract

The potential anticancer activity of different silver nanoformulations is increasingly recognized. In the present work, we use the model of 4T1 tumor in BALB/ccmdb immunocompetent mice to analyze the impact of citrate- and PEG-coated silver nanoparticles (AgNPs) on the development and metastatic potential of breast cancer. One group of mice was intragastrically administered with 1 mg/kg body weight (b.w.) of AgNPs daily from day 1 to day 14 after cancer cells implantation (total dose 14 mg/kg b.w.). The second group was intravenously administered twice with 1 or 5 mg/kg b.w. of AgNPs. A tendency for lowering tumor volume on day 21 (mean volumes 491.31, 428.88, and 386.83 mm

Indexed as

AgNPscancermetastasissilver nanoparticles

Identifiers

PMID35683135
PMCPMC9181667
OpenAlexW4281734322

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.