Evidence map›Paper›PMID 35683016›Full record

ArticleInternational journal of molecular sciences2022

Nerve Growth Factor (NGF) as Partaker in the Modulation of UV-Response in Cultured Human Conjunctival Fibroblasts.

Graziana Esposito, Bijorn Omar Balzamino, Maria Luisa Rocco, Luigi Aloe, Alessandra Micera

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Graziana EspositoResearch and Development Laboratory for Biochemical, Molecular and Cellular Applications in Ophthalmological Science, IRCCS-Fondazione Bietti, 00198 Rome, Italy.
Bijorn Omar BalzaminoResearch and Development Laboratory for Biochemical, Molecular and Cellular Applications in Ophthalmological Science, IRCCS-Fondazione Bietti, 00198 Rome, Italy.ORCID 0000-0002-2254-1647
Maria Luisa RoccoInstitute of Cell Biology and Neurobiology, CNR, 00143 Rome, Italy.
Luigi AloeFondazione IRET, 40064 Bologna, Italy.
Alessandra MiceraResearch and Development Laboratory for Biochemical, Molecular and Cellular Applications in Ophthalmological Science, IRCCS-Fondazione Bietti, 00198 Rome, Italy.ORCID 0000-0002-9375-6071
Fondazione G.B. Bietti · ITAssociazione Italiana Vulvodinia Onlus · ITInstitute of Cell Biology and Neurobiology · IT

Funding

Ministero della Salute RC2765943
6 · The paper itself

Abstract

Corroborating data sustain the pleiotropic effect of nerve growth factor (NGF) in the protection of the visual system from dangerous stimuli, including ultraviolet (UV). Since UV exposure might promote ocular surface changes (conjunctival inflammation and matrix rearrangement), as previously reported from in vivo studies sustaining some protective NGF effects, in vitro cultures of human conjunctival fibroblasts (FBs) were developed and exposed to a single UV exposure over 15 min (0.277 W/m

Indexed as

Nerve Growth FactorReceptor, trkAFibroblastsHumansInterleukin-33Interleukin-8Kelch-Like ECH-Associated Protein 1NF-E2-Related Factor 2Receptor, Nerve Growth FactorReceptors, Nerve Growth FactorInterleukin-33Interleukin-8Kelch-Like ECH-Associated Protein 1Nerve Growth FactorNF-E2-Related Factor 2Receptor, Nerve Growth FactorReceptors, Nerve Growth FactorReceptor, trkAconjunctival fibroblastsepigeneticsin vitroneuroprotectionNGFpara-inflammationultraviolet radiation

Identifiers

PMID35683016
PMCPMC9181148
OpenAlexW4281714819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.