Evidence map›Paper›PMID 35682970›Full record

ArticleInternational journal of molecular sciences2022

The Minus-End-Directed Kinesin OsDLK Shuttles to the Nucleus and Modulates the Expression of Cold-Box Factor 4.

Xiaolu Xu, Sabine Hummel, Klaus Harter, Üner Kolukisaoglu, Michael Riemann, Peter Nick

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Cold-Induced Nuclear Import of CBF4 Regulates Freezing Tolerance.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xiaolu XuMolecular Cell Biology, Botanical Institute, Karlsruhe Institute of Technology, Fritz-Haber-Weg 4, D-76131 Karlsruhe, Germany.ORCID 0000-0002-4968-041X
Sabine HummelCenter for Plant Molecular Biology (ZMBP), University of Tübingen, Auf der Morgenstelle 32, D-72076 Tübingen, Germany.
Klaus HarterCenter for Plant Molecular Biology (ZMBP), University of Tübingen, Auf der Morgenstelle 32, D-72076 Tübingen, Germany.ORCID 0000-0002-2150-6970
Üner KolukisaogluCenter for Plant Molecular Biology (ZMBP), University of Tübingen, Auf der Morgenstelle 32, D-72076 Tübingen, Germany.ORCID 0000-0002-8656-5963
Michael RiemannMolecular Cell Biology, Botanical Institute, Karlsruhe Institute of Technology, Fritz-Haber-Weg 4, D-76131 Karlsruhe, Germany.ORCID 0000-0003-0287-2112
Peter NickMolecular Cell Biology, Botanical Institute, Karlsruhe Institute of Technology, Fritz-Haber-Weg 4, D-76131 Karlsruhe, Germany.ORCID 0000-0002-0763-4175
Karlsruhe Institute of Technology · DEUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transition to terrestrial plants was accompanied by a progressive loss of microtubule minus-end-directed dynein motors. Instead, the minus-end-directed class-XIV kinesins expanded considerably, likely related to novel functions. One of these motors, OsDLK (Dual Localisation Kinesin from rice), decorates cortical microtubules but moves into the nucleus in response to cold stress. This analysis of loss-of-function mutants in rice indicates that OsDLK participates in cell elongation during development. Since OsDLK harbours both a nuclear localisation signal and a putative leucin zipper, we asked whether the cold-induced import of OsDLK into the nucleus might correlate with specific DNA binding. Conducting a DPI-ELISA screen with recombinant OsDLKT (lacking the motor domain), we identified the Opaque2 motif as the most promising candidate. This motif is present in the promoter of

Indexed as

KinesinsOryzaCell NucleusDyneinsMicrotubulesDyneinsKinesinsCold-Box Factor 4cold stresskinesinmicrotubulesnuclear importrice (Oryza sativa L.)

Identifiers

PMID35682970
PMCPMC9181729
OpenAlexW4281726415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.