Evidence map›Paper›PMID 35682904›Full record

ArticleInternational journal of molecular sciences2022

A Universal Fluorescent Immunochromatography Assay Based on Quantum Dot Nanoparticles for the Rapid Detection of Specific Antibodies against SARS-CoV-2 Nucleocapsid Protein.

Zehui Li, Aiping Wang, Jingming Zhou, Yumei Chen, Hongliang Liu, Yankai Liu, Ying Zhang, Peiyang Ding, Xifang Zhu, Chao Liang and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Recent Trends in Lateral Flow Immunoassays with Optical Nanoparticles.International journal of molecular sciences · 2023
    Review
  4. Article
  5. Rapid detection of SARS-CoV-2: The gradual boom of lateral flow immunoassay.Frontiers in bioengineering and biotechnology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Zehui LiSchool of Life Science, Zhengzhou University, Zhengzhou 450001, China.
Aiping WangSchool of Life Science, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0003-1661-8174
Jingming ZhouSchool of Life Science, Zhengzhou University, Zhengzhou 450001, China.
Yumei ChenSchool of Life Science, Zhengzhou University, Zhengzhou 450001, China.
Hongliang LiuSchool of Life Science, Zhengzhou University, Zhengzhou 450001, China.
Yankai LiuSchool of Life Science, Zhengzhou University, Zhengzhou 450001, China.
Ying ZhangSchool of Life Science, Zhengzhou University, Zhengzhou 450001, China.
Peiyang DingSchool of Life Science, Zhengzhou University, Zhengzhou 450001, China.
Xifang ZhuSchool of Life Science, Zhengzhou University, Zhengzhou 450001, China.
Chao LiangSchool of Life Science, Zhengzhou University, Zhengzhou 450001, China.
Yanhua QiSchool of Life Science, Zhengzhou University, Zhengzhou 450001, China.
Enping LiuSchool of Life Science, Zhengzhou University, Zhengzhou 450001, China.
Gaiping ZhangSchool of Life Science, Zhengzhou University, Zhengzhou 450001, China.
Zhengzhou University · CNPeking University · CN

Funding

Emergency Scientific Research on Epidemic Prevention and Control of Henan Province 211100310200National Natural Science Foundation of China 32072944
6 · The paper itself

Abstract

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the pathogenic agent leading to COVID-19. Due to high speed of transmission and mutation rates, universal diagnosis and appropriate prevention are still urgently needed. The nucleocapsid protein of SARS-CoV-2 is considered more conserved than spike proteins and is abundant during the virus' life cycle, making it suitable for diagnostic applications. Here, we designed and developed a fluorescent immunochromatography assay (FICA) for the rapid detection of SARS-CoV-2-specific antibodies using ZnCdSe/ZnS QDs-conjugated nucleocapsid (N) proteins as probes. The nucleocapsid protein was expressed in

Indexed as

COVID-19Quantum DotsAnimalsAntibodies, ViralChromatography, AffinityNucleocapsid ProteinsSARS-CoV-2Sensitivity and SpecificityAntibodies, ViralNucleocapsid Proteinsfluorescent immunochromatography assaynucleocapsid proteinpoint-of-care detectionquantum dotsSARS-CoV-2

Identifiers

PMID35682904
PMCPMC9180975
OpenAlexW4281976652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.