Evidence map›Paper›PMID 35682873›Full record

ArticleInternational journal of molecular sciences2022

A Possible Way to Relate the Effects of SARS-CoV-2-Induced Changes in Transferrin to Severe COVID-19-Associated Diseases.

Elek Telek, Zoltán Ujfalusi, Gábor Kemenesi, Brigitta Zana, Ferenc Jakab, Gabriella Hild, András Lukács, Gábor Hild

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Association of COVID with Mycosis in General.Infectious disorders drug targets · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Elek TelekDepartment of Biophysics, Medical School, University of Pécs, Szigeti Str. 12, H-7624 Pécs, Hungary.ORCID 0000-0003-0396-4799
Zoltán UjfalusiDepartment of Biophysics, Medical School, University of Pécs, Szigeti Str. 12, H-7624 Pécs, Hungary.ORCID 0000-0001-5936-7286
Gábor KemenesiSzentágothai Research Centre, Virological Research Group, University of Pécs, Ifjúság Str. 20, H-7624 Pécs, Hungary.ORCID 0000-0001-9775-3065
Brigitta ZanaSzentágothai Research Centre, Virological Research Group, University of Pécs, Ifjúság Str. 20, H-7624 Pécs, Hungary.ORCID 0000-0002-3503-8901
Ferenc JakabSzentágothai Research Centre, Virological Research Group, University of Pécs, Ifjúság Str. 20, H-7624 Pécs, Hungary.
Gabriella HildLanguages for Biomedical Purposes and Communication, Medical School, University of Pécs, Szigeti Str. 12, H-7624 Pécs, Hungary.
András LukácsDepartment of Biophysics, Medical School, University of Pécs, Szigeti Str. 12, H-7624 Pécs, Hungary.
Gábor HildDepartment of Biophysics, Medical School, University of Pécs, Szigeti Str. 12, H-7624 Pécs, Hungary.
University of Pecs · HU

Funding

University of Pecs EFOP-3.6.3.VEKOP-16-2017-00009University of Pecs KA-2019-40University of Pecs KA-2020-09University of Pecs KA-2022-09
6 · The paper itself

Abstract

SARS-CoV-2 infections are responsible for the COVID-19 pandemic. Transferrin has been found to explain the link between diseases associated with impaired iron transport and COVID-19 infection. The effect of SARS-CoV-2 on human whole blood was studied by differential scanning calorimetry. The analysis of the thermal transition curves showed that the melting temperature of the transferrin-related peak decreased in the presence of SARS-CoV-2. The ratio of the under-curve area of the two main peaks was greatly affected, while the total enthalpy of the heat denaturation remained nearly unchanged in the presence of the virus. These results indicate that SARS-CoV-2, through binding to transferrin, may influence its Fe

Indexed as

COVID-19SARS-CoV-2HumansIronPandemicsTransferrinIronTransferrincalorimetryCOVID-19human whole bloodSARS-CoV-2transferrin

Identifiers

PMID35682873
PMCPMC9181396
OpenAlexW4281676710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.