Evidence map›Paper›PMID 35682834›Full record

ArticleInternational journal of molecular sciences2022

Persistent Infection of a Canine Histiocytic Sarcoma Cell Line with Attenuated Canine Distemper Virus Expressing Vasostatin or Granulocyte-Macrophage Colony-Stimulating Factor.

Katarzyna Marek, Federico Armando, Vanessa Maria Nippold, Karl Rohn, Philippe Plattet, Graham Brogden, Gisa Gerold, Wolfgang Baumgärtner, Christina Puff

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Katarzyna MarekDepartment of Pathology, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.
Federico ArmandoDepartment of Pathology, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.ORCID 0000-0002-2578-4409
Vanessa Maria NippoldDepartment of Pathology, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.
Karl RohnInstitute for Biometry, Epidemiology and Information Processing, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.
Philippe PlattetDivision of Experimental Clinical Research, Vetsuisse University Bern, 3012 Bern, Switzerland.
Graham BrogdenDepartment of Biochemistry, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.
Gisa GeroldDepartment of Biochemistry, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.ORCID 0000-0002-1326-5038
Wolfgang BaumgärtnerDepartment of Pathology, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.ORCID 0000-0001-8151-5644
Christina PuffDepartment of Pathology, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.ORCID 0000-0002-2592-6868
University of Veterinary Medicine Hannover, Foundation · DEUniversity of Bern · CH

Funding

Brigitte und Prof. Dr Reiner Müller-Peddinghaus Foundation Scholarship Katarzyna MarekDeutsche Forschungsgemeinschaft (DFG, German Research Foundation) and University of Veterinary Medicine Hannover, Foundation. LE 824/10-1 "Open Access Publication Costs"
6 · The paper itself

Abstract

Canine histiocytic sarcoma (HS) represents a neoplasia with poor prognosis. Due to the high metastatic rate of HS, there is urgency to improve treatment options and to prevent tumor metastases. Canine distemper virus (CDV) is a single-stranded negative-sense RNA (ssRNA (-)) virus with potentially oncolytic properties. Moreover, vasostatin and granulocyte-macrophage colony-stimulating factor (GM-CSF) are attractive molecules in cancer therapy research because of their anti-angiogenetic properties and potential modulation of the tumor microenvironment. In the present study, an

Indexed as

Distemper Virus, CanineHistiocytic SarcomaAnimalsCalreticulinCell LineDogsGranulocyte-Macrophage Colony-Stimulating FactorNeonPeptide FragmentsPersistent InfectionRNA, MessengerTumor MicroenvironmentCalreticulinGranulocyte-Macrophage Colony-Stimulating FactorNeonPeptide FragmentsRNA, Messengervasostatincanine distemper viruscanine histiocytic sarcomaCDV-OnderstepoortDH82genetically engineered virusesGM-CSFmNeonGreenvasostatinviral oncolysis

Identifiers

PMID35682834
PMCPMC9181094
OpenAlexW4281990596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.