Evidence map›Paper›PMID 35682795›Full record

ReviewInternational journal of molecular sciences2022

Thirty Years' History since the Discovery of Pax6: From Central Nervous System Development to Neurodevelopmental Disorders.

Shohei Ochi, Shyu Manabe, Takako Kikkawa, Noriko Osumi

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
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  9. DuplicatedBiology · 2025
    Article
  10. Analysis ofInternational journal of molecular sciences · 2025
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  20. A Whole-Brain Topographic Ontology.Annual review of neuroscience · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shohei OchiDepartment of Developmental Neuroscience, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.ORCID 0000-0003-3602-439X
Shyu ManabeDepartment of Developmental Neuroscience, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Takako KikkawaDepartment of Developmental Neuroscience, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.ORCID 0000-0002-6643-8289
Noriko OsumiDepartment of Developmental Neuroscience, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Tohoku University · JP

Funding

Japan Agency for Medical Research and Development JP21wm0425003Japan Society for the Promotion of Science JP30884217
6 · The paper itself

Abstract

Pax6 is a sequence-specific DNA binding transcription factor that positively and negatively regulates transcription and is expressed in multiple cell types in the developing and adult central nervous system (CNS). As indicated by the morphological and functional abnormalities in spontaneous

Indexed as

Autism Spectrum DisorderIntellectual DisabilityNeurodevelopmental DisordersAnimalsEye ProteinsHomeodomain ProteinsHumansMicePaired Box Transcription FactorsPAX6 Transcription FactorRepressor ProteinsTelencephalonEye ProteinsHomeodomain ProteinsPaired Box Transcription FactorsPAX6 protein, humanPax6 protein, mousePAX6 Transcription FactorRepressor Proteinsautism spectrum disorderbrain patterningcell proliferationcentral nervous systemmouseneural differentiationneural stem cellsPax6ratSey mutant

Identifiers

PMID35682795
PMCPMC9181425
OpenAlexW4281901791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.