Evidence map›Paper›PMID 35682786›Full record

ArticleInternational journal of molecular sciences2022

Curvicollide D Isolated from the Fungus

Matilde Ortiz-Gonzalez, Ignacio Pérez-Victoria, Inmaculada Ramirez-Macias, Nuria de Pedro, Angel Linde-Rodriguez, Víctor González-Menéndez, Victoria Sanchez-Martin, Jesús Martín, Ana Soriano-Lerma, Olga Genilloud and 8 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

Matilde Ortiz-GonzalezCenter for Intensive Mediterranean Agrosystems and Agri-Food Biotechnology (CIAIMBITAL), University of Almeria, 04001 Almería, Spain.ORCID 0000-0001-9977-5735
Ignacio Pérez-VictoriaFundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Avenida del Conocimiento 34, 18016 Granada, Spain.ORCID 0000-0002-4556-688X
Inmaculada Ramirez-MaciasGENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government, PTS Granada-Avenida de la Ilustración, 18016 Granada, Spain.ORCID 0000-0001-9559-9180
Nuria de PedroFundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Avenida del Conocimiento 34, 18016 Granada, Spain.
Angel Linde-RodriguezGENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government, PTS Granada-Avenida de la Ilustración, 18016 Granada, Spain.ORCID 0000-0001-5954-8562
Víctor González-MenéndezFundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Avenida del Conocimiento 34, 18016 Granada, Spain.ORCID 0000-0001-9859-6284
Victoria Sanchez-MartinGENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government, PTS Granada-Avenida de la Ilustración, 18016 Granada, Spain.ORCID 0000-0001-6870-3659
Jesús MartínFundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Avenida del Conocimiento 34, 18016 Granada, Spain.
Ana Soriano-LermaGENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government, PTS Granada-Avenida de la Ilustración, 18016 Granada, Spain.
Olga GenilloudFundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Avenida del Conocimiento 34, 18016 Granada, Spain.ORCID 0000-0002-4202-1219
Virginia Perez-CarrascoGENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government, PTS Granada-Avenida de la Ilustración, 18016 Granada, Spain.
Francisca VicenteFundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Avenida del Conocimiento 34, 18016 Granada, Spain.ORCID 0000-0003-3198-9205
José MaceiraGENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government, PTS Granada-Avenida de la Ilustración, 18016 Granada, Spain.ORCID 0000-0002-6178-1846
Carlos A Rodrígues-PovedaGENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government, PTS Granada-Avenida de la Ilustración, 18016 Granada, Spain.
José María Navarro-MaríMicrobiology Unit, Biosanitary Research Institute IBS.Granada, University Hospital Virgen de las Nieves, 18014 Granada, Spain.ORCID 0000-0002-5227-5167
Fernando ReyesFundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Avenida del Conocimiento 34, 18016 Granada, Spain.ORCID 0000-0003-1607-5106
Miguel SorianoCenter for Intensive Mediterranean Agrosystems and Agri-Food Biotechnology (CIAIMBITAL), University of Almeria, 04001 Almería, Spain.ORCID 0000-0002-1838-3615
Jose A Garcia-SalcedoGENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada, Andalusian Regional Government, PTS Granada-Avenida de la Ilustración, 18016 Granada, Spain.ORCID 0000-0003-3399-1835
Fundación Medina · ESInstituto de Investigación Biosanitaria de Granada · ESPfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research · ESUniversidad de Granada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleeping sickness or African trypanosomiasis is a serious health concern with an added socio-economic impact in sub-Saharan Africa due to direct infection in both humans and their domestic livestock. There is no vaccine available against African trypanosomes and its treatment relies only on chemotherapy. Although the current drugs are effective, most of them are far from the modern concept of a drug in terms of toxicity, specificity and therapeutic regime. In a search for new molecules with trypanocidal activity, a high throughput screening of 2000 microbial extracts was performed. Fractionation of one of these extracts, belonging to a culture of the fungus

Indexed as

Trypanocidal AgentsTrypanosoma brucei bruceiTrypanosomiasis, AfricanAnimalsFungiHumansTrypanocidal AgentsAfrican trypanosomiasiscurvicollide Dnatural productsnew trypanocidal molecule

Identifiers

PMID35682786
PMCPMC9181715
OpenAlexW4281650301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.