Evidence map›Paper›PMID 35682782›Full record

ArticleInternational journal of molecular sciences2022

Picrasidine I Triggers Heme Oxygenase-1-Induced Apoptosis in Nasopharyngeal Carcinoma Cells via ERK and Akt Signaling Pathways.

Hsin-Yu Ho, Ping-Ju Chen, Yi-Ching Chuang, Yu-Sheng Lo, Chia-Chieh Lin, Ming-Ju Hsieh, Mu-Kuan Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Picrasidine J, a Dimeric β-Carboline-Type Alkaloid fromInternational journal of molecular sciences · 2023
    Article
  4. Hemoxygenase-1 Promotes Head and Neck Cancer Cell Viability.Antioxidants (Basel, Switzerland) · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hsin-Yu HoOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.ORCID 0000-0002-8496-1313
Ping-Ju ChenDepartment of Dentistry, Changhua Christian Hospital, Changhua 500, Taiwan.
Yi-Ching ChuangOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.
Yu-Sheng LoOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.
Chia-Chieh LinOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.ORCID 0000-0002-2746-4054
Ming-Ju HsiehOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.ORCID 0000-0001-9726-3234
Mu-Kuan ChenDepartment of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, Changhua 500, Taiwan.
Changhua Christian Hospital · TWNational Chung Hsing University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nasopharyngeal carcinoma (NPC) has a higher incidence in Taiwan than worldwide. Although it is a radiosensitive malignancy, cancer recurrence is still high in the advanced stages because of its ability to induce lymph node metastasis. Picrasidine I from

Indexed as

Nasopharyngeal NeoplasmsProto-Oncogene Proteins c-aktApoptosisCarbolinesCell Line, TumorCell ProliferationExtracellular Signal-Regulated MAP KinasesHeme Oxygenase-1HumansNasopharyngeal CarcinomaNeoplasm Recurrence, LocalSignal TransductionCarbolinesExtracellular Signal-Regulated MAP KinasesHeme Oxygenase-1picrasidine IProto-Oncogene Proteins c-aktapoptosisheme oxygenase-1mitogen-activated protein kinase (MAPK) pathwaypicrasidine I

Identifiers

PMID35682782
PMCPMC9181417
OpenAlexW4281773958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.