Evidence map›Paper›PMID 35682766›Full record

ArticleInternational journal of molecular sciences2022

Vitamin B6 Deficiency Promotes Loss of Heterozygosity (LOH) at the Drosophila warts (wts) Locus

Eleonora Gnocchini, Eleonora Pilesi, Ludovica Schiano, Fiammetta Vernì

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. From Fly to Human: Translational Relevance ofInternational journal of molecular sciences · 2026
    Review
  3. Article
  4. Article
  5. Vitamin B6 deficiency produces metabolic alterations in Drosophila.Metabolomics : Official journal of the Metabolomic Society · 2025
    Article
  6. Article
  7. Plastic Fly: WhatInternational journal of molecular sciences · 2024
    Article
  8. Article
  9. Review
  10. DNA Damage Response (DDR) and DNA Repair.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eleonora GnocchiniDepartment of Biology and Biotechnology "Charles Darwin", Sapienza University, 00185 Rome, Italy.
Eleonora PilesiDepartment of Biology and Biotechnology "Charles Darwin", Sapienza University, 00185 Rome, Italy.
Ludovica SchianoDepartment of Biology and Biotechnology "Charles Darwin", Sapienza University, 00185 Rome, Italy.
Fiammetta VernìDepartment of Biology and Biotechnology "Charles Darwin", Sapienza University, 00185 Rome, Italy.

Funding

Sapienza University of Rome RP120172838CFF6C
6 · The paper itself

Abstract

The active form of vitamin B6, pyridoxal 5'-phosphate (PLP), is a cofactor for more than 200 enzymes involved in many metabolic pathways. Moreover, PLP has antioxidant properties and quenches the reactive oxygen species (ROS). Accordingly, PLP deficiency causes chromosome aberrations in

Indexed as

Vitamin B 6 DeficiencyWartsAnimalsDrosophilaLoss of HeterozygosityPyridoxal PhosphateVitamin B 6Pyridoxal PhosphateVitamin B 6Drosophilaloss of heterozygosity (LOH)mitotic recombinationpyridoxal 5′ phosphate (PLP)vitamin B6warts

Identifiers

PMID35682766
PMCPMC9181336

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.