Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
2 citing papers in PubMed, 4 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
7 authors at 1 institution in 1 country.
Ryan M MarquardtDepartment of Obstetrics, Gynecology and Reproductive Biology, Michigan State University, Grand Rapids, MI 49503, USA.ORCID 0000-0002-6597-4506
Soo Hyun AhnDepartment of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0001-9541-5281
Jake J ReskeDepartment of Obstetrics, Gynecology and Reproductive Biology, Michigan State University, Grand Rapids, MI 49503, USA.
Ronald L ChandlerDepartment of Obstetrics, Gynecology and Reproductive Biology, Michigan State University, Grand Rapids, MI 49503, USA.
Margaret G PetroffCell and Molecular Biology Program, College of Natural Science, Michigan State University, East Lansing, MI 48824, USA.
Tae Hoon KimDepartment of Obstetrics, Gynecology and Reproductive Biology, Michigan State University, Grand Rapids, MI 49503, USA.
Jae-Wook JeongDepartment of Obstetrics, Gynecology and Reproductive Biology, Michigan State University, Grand Rapids, MI 49503, USA.ORCID 0000-0002-5368-6478
Michigan State University · US
Funding
Epigenetic regulation of receptive endometriumR01HD102170 · NICHD · UNIVERSITY OF MISSOURI-COLUMBIA · PI JEONG, JAE-WOOK, LESSEY, BRUCE A · 2021 to 2025
$2.9M
Molecular mechanisms of endometrial progesterone resistanceR01HD101243 · NICHD · UNIVERSITY OF MISSOURI-COLUMBIA · PI JEONG, JAE-WOOK · 2020 to 2024
$2.6M
Reproductive and Developmental Sciences Training Program - T32T32HD087166 · NICHD · MICHIGAN STATE UNIVERSITY · PI Ronald L Chandler, Keith E Latham · 2016 to 2026
$2.5M
Epigenetic regulatory mechanisms and therapeutic opportunities in endometriosisR01HD103617 · NICHD · MICHIGAN STATE UNIVERSITY · PI CHANDLER, RONALD L · 2021 to 2025
$1.7M
Risk factors for early pregnancy lossR01HD084478 · NICHD · MICHIGAN STATE UNIVERSITY · PI JEONG, JAE-WOOK · 2016 to 2020
$1.6M
Role of chromatin remodeling and cell signaling in endometriosis etiologyR21HD099383 · NICHD · MICHIGAN STATE UNIVERSITY · PI CHANDLER, RONALD L · 2019 to 2020
$430k
The role of ARID1A in endometriosis-related infertilityF31HD101207 · NICHD · MICHIGAN STATE UNIVERSITY · PI MARQUARDT, RYAN · 2020 to 2021
$66k
Eunice Kennedy Shriver National Institute of Child Health and Human Development F31HD101207Eunice Kennedy Shriver National Institute of Child Health and Human Development R01HD084478Eunice Kennedy Shriver National Institute of Child Health and Human Development R01HD101243Eunice Kennedy Shriver National Institute of Child Health and Human Development R01HD102170Eunice Kennedy Shriver National Institute of Child Health and Human Development T32HD087166NICHD NIH HHS F31 HD101207NICHD NIH HHS R01 HD084478NICHD NIH HHS R01 HD101243NICHD NIH HHS R01 HD102170NICHD NIH HHS R01 HD103617NICHD NIH HHS R21 HD099383NICHD NIH HHS T32 HD087166
6 · The paper itself
Abstract
A growing body of work suggests epigenetic dysregulation contributes to endometriosis pathophysiology and female infertility. The chromatin remodeling complex subunit AT-rich interaction domain 1A (ARID1A) must be properly expressed to maintain normal uterine function. Endometrial epithelial ARID1A is indispensable for pregnancy establishment in mice through regulation of endometrial gland function; however, ARID1A expression is decreased in infertile women with endometriosis. We hypothesized that ARID1A performs critical operations in the endometrial epithelium necessary for fertility besides maintaining gland function. To identify alterations in uterine gene expression resulting from loss of epithelial ARID1A, we performed RNA-sequencing analysis on pre-implantation uteri from
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Endometrial Epithelial ARID1A Is Required for Uterine Immune Homeostasis during Early Pregnancy. · full record | OpenQuestion