Evidence map›Paper›PMID 35682734›Full record

ArticleInternational journal of molecular sciences2022

Mitochondrial rRNA Methylation by Mettl15 Contributes to the Exercise and Learning Capability in Mice.

Olga A Averina, Ivan G Laptev, Mariia A Emelianova, Oleg A Permyakov, Sofia S Mariasina, Alyona I Nikiforova, Vasily N Manskikh, Olga O Grigorieva, Anastasia K Bolikhova, Gennady A Kalabin and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. METTL Family in Healthy and Disease.Molecular biomedicine · 2024
    Review
  4. Article
  5. Article
  6. Kidney-Related Function of Mitochondrial Protein Mitoregulin.International journal of molecular sciences · 2023
    Article
  7. METTLing in Stem Cell and Cancer Biology.Stem cell reviews and reports · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Olga A AverinaInstitute of Functional Genomics, Lomonosov Moscow State University, 119991 Moscow, Russia.
Ivan G LaptevBelozersky Institute of Physico-Chemical Biology, Lomonosov Mosco16w State University, 119991 Moscow, Russia.
Mariia A EmelianovaCenter of Life Sciences, Skolkovo Institute of Science and Technology, 121205 Moscow, Russia.
Oleg A PermyakovInstitute of Functional Genomics, Lomonosov Moscow State University, 119991 Moscow, Russia.
Sofia S MariasinaInstitute of Functional Genomics, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0002-9190-1298
Alyona I NikiforovaInstitute of Mitoengineering, Lomonosov Moscow State University, 119234 Moscow, Russia.
Vasily N ManskikhBelozersky Institute of Physico-Chemical Biology, Lomonosov Mosco16w State University, 119991 Moscow, Russia.
Olga O GrigorievaInstitute of Functional Genomics, Lomonosov Moscow State University, 119991 Moscow, Russia.
Anastasia K BolikhovaFaculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119234 Moscow, Russia.
Gennady A KalabinPharmacy Resource Center, Peoples' Friendship University of Russia (RUDN), 117198 Moscow, Russia.
Olga A DontsovaBelozersky Institute of Physico-Chemical Biology, Lomonosov Mosco16w State University, 119991 Moscow, Russia.
Petr V SergievInstitute of Functional Genomics, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0001-8866-1863
Lomonosov Moscow State University · RUSkolkovo Institute of Science and Technology · RUPeoples' Friendship University of Russia · RU

Funding

Lomonosov Moscow State University Leading scientific school molecular technology of biological systems and synthetic biologyRussian Foundation for Basic Research 20-04-00736Russian Science Foundation 19-14-00043Russian Science Foundation 19-14-00115Russian Science Foundation 21-64-00006
6 · The paper itself

Abstract

Mitochondrial translation is a unique relic of the symbiotic origin of the organelle. Alterations of its components cause a number of severe human diseases. Hereby we report a study of mice devoid of Mettl15 mitochondrial 12S rRNA methyltransferase, responsible for the formation of m

Indexed as

MitochondriaMitochondrial RibosomesAnimalsMethylationMethyltransferasesMiceMitochondrial ProteinsRNA Processing, Post-TranscriptionalMethyltransferasesMitochondrial Proteinsknockout micemethylationmitochondriarRNAtranslation

Identifiers

PMID35682734
PMCPMC9181494
OpenAlexW4281652203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.