Evidence map›Paper›PMID 35682630›Full record

ArticleInternational journal of molecular sciences2022

Surface Chemical and Morphological Analysis of Chitosan/1,3-β-d-Glucan Polysaccharide Films Cross-Linked at 90 °C.

Barbara Gieroba, Anna Sroka-Bartnicka, Paulina Kazimierczak, Grzegorz Kalisz, Agnieszka Lewalska-Graczyk, Vladyslav Vivcharenko, Robert Nowakowski, Izabela S Pieta, Agata Przekora

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  16. Review
  17. FT-IR Method Limitations for β-Glucan Analysis.Molecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Barbara GierobaIndependent Unit of Spectroscopy and Chemical Imaging, Chair of Biomedical Sciences, Medical University of Lublin, Chodzki 4a, 20-093 Lublin, Poland.ORCID 0000-0001-8549-9848
Anna Sroka-BartnickaIndependent Unit of Spectroscopy and Chemical Imaging, Chair of Biomedical Sciences, Medical University of Lublin, Chodzki 4a, 20-093 Lublin, Poland.ORCID 0000-0003-0739-3567
Paulina KazimierczakIndependent Unit of Tissue Engineering and Regenerative Medicine, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.ORCID 0000-0002-5893-7168
Grzegorz KaliszIndependent Unit of Spectroscopy and Chemical Imaging, Chair of Biomedical Sciences, Medical University of Lublin, Chodzki 4a, 20-093 Lublin, Poland.ORCID 0000-0001-5159-6308
Agnieszka Lewalska-GraczykInstitute of Physical Chemistry Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.ORCID 0000-0003-4902-6853
Vladyslav VivcharenkoIndependent Unit of Tissue Engineering and Regenerative Medicine, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.ORCID 0000-0002-1526-686X
Robert NowakowskiInstitute of Physical Chemistry Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.ORCID 0000-0002-8103-3044
Izabela S PietaInstitute of Physical Chemistry Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.ORCID 0000-0002-3394-7116
Agata PrzekoraIndependent Unit of Tissue Engineering and Regenerative Medicine, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.ORCID 0000-0002-6076-1309

Funding

Foundation for Polish Science P.K. has received annual support (scholarship - START) from the Foundation for Polish Science (FNP)Foundation for Polish Science POIR.04.04.00-00-4398/17-00Foundation for Polish Science REINTEGRATION/2016-1/5Medical University of Lublin DS3/2022
6 · The paper itself

Abstract

The cross-linking temperature of polymers may affect the surface characteristics and molecular arrangement, which are responsible for their mechanical and physico-chemical properties. The aim of this research was to determine and explain in detail the mechanism of unit interlinkage of two-component chitosan/1,3-β-d-glucan matrices gelled at 90 °C. This required identifying functional groups interacting with each other and assessing surface topography providing material chemical composition. For this purpose, various spectroscopic and microscopic approaches, such as attenuated total reflection Fourier transform infrared spectroscopy (ATR FT-IR), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM), were applied. The results indicate the involvement mainly of the C-C and C-H groups and C=O⋯HN moieties in the process of biomaterial polymerization. Strong chemical interactions and ionocovalent bonds between the N-glucosamine moieties of chitosan and 1,3-β-d-glucan units were demonstrated, which was also reflected in the uniform surface of the sample without segregation. These unique properties, hybrid character and proper cell response may imply the potential application of studied biomaterial as biocompatible scaffolds used in regenerative medicine, especially in bone restoration and/or wound healing.

Indexed as

ChitosanBiocompatible MaterialsGlucansPolymersSpectroscopy, Fourier Transform InfraredSurface PropertiesBiocompatible MaterialsChitosanGlucansPolymers1,3-β-d-glucanchitosancross-linked polymerspolysaccharide biomaterialsstructural analysissurface properties

Identifiers

PMID35682630
PMCPMC9180171

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.