Evidence map›Paper›PMID 35682570›Full record

ArticleInternational journal of molecular sciences2022

Beneficial Effects of Linseed Supplementation on Gut Mucosa-Associated Microbiota in a Physically Active Mouse Model of Crohn's Disease.

Claire Plissonneau, Adeline Sivignon, Benoit Chassaing, Frederic Capel, Vincent Martin, Monique Etienne, Ivan Wawrzyniak, Pierre Chausse, Frederic Dutheil, Guillaume Mairesse and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Special Issue "Dietary Bioactive Components in Inflammatory Bowel Disease".International journal of molecular sciences · 2024
    Article
  4. Review
  5. Review
  6. Crohn's disease: Why the ileum?World journal of gastroenterology · 2023
    Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Claire PlissonneauMicrobes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), UMR 1071 Inserm, USC-INRAE 2018, Université Clermont Auvergne, CRNH Auvergne, 63000 Clermont-Ferrand, France.ORCID 0000-0002-0169-9533
Adeline SivignonLaboratoire des Adaptations Métaboliques à l'Exercice en Conditions Physiologiques et Pathologiques (AME2P), Université Clermont Auvergne, CRNH Auvergne, 63000 Clermont-Ferrand, France.
Benoit ChassaingInserm U1016, Team ''Mucosal Microbiota in Chronic Inflammatory Diseases'', CNRS UMR 8104, Université de Paris, 75014 Paris, France.ORCID 0000-0002-4285-769X
Frederic CapelUnité de Nutrition Humaine (UNH), INRAE, Université Clermont Auvergne, CRNH Auvergne, 63000 Clermont-Ferrand, France.ORCID 0000-0002-0133-0277
Vincent MartinLaboratoire des Adaptations Métaboliques à l'Exercice en Conditions Physiologiques et Pathologiques (AME2P), Université Clermont Auvergne, CRNH Auvergne, 63000 Clermont-Ferrand, France.ORCID 0000-0002-6681-1610
Monique EtienneLaboratoire des Adaptations Métaboliques à l'Exercice en Conditions Physiologiques et Pathologiques (AME2P), Université Clermont Auvergne, CRNH Auvergne, 63000 Clermont-Ferrand, France.
Ivan WawrzyniakLaboratoire Microorganismes, Génome et Environnement (LMGE), CNRS, Université Clermont Auvergne, 63000 Clermont-Ferrand, France.ORCID 0000-0002-5362-6117
Pierre ChausseLaboratoire de Psychologie Sociale et Cognitive (LaPSCo), CNRS UMR 6024, Physiological and Psychosocial Stress, University Hospital of Clermont-Ferrand, Université Clermont Auvergne, 63000 Clermont-Ferrand, France.
Frederic DutheilLaboratoire de Psychologie Sociale et Cognitive (LaPSCo), CNRS UMR 6024, Physiological and Psychosocial Stress, University Hospital of Clermont-Ferrand, Université Clermont Auvergne, 63000 Clermont-Ferrand, France.
Guillaume MairesseValorex, La Messayais, 35210 Combourtillé, France.
Guillaume ChesneauValorex, La Messayais, 35210 Combourtillé, France.
Nathalie BoisseauLaboratoire des Adaptations Métaboliques à l'Exercice en Conditions Physiologiques et Pathologiques (AME2P), Université Clermont Auvergne, CRNH Auvergne, 63000 Clermont-Ferrand, France.ORCID 0000-0003-2835-1163
Nicolas BarnichMicrobes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), UMR 1071 Inserm, USC-INRAE 2018, Université Clermont Auvergne, CRNH Auvergne, 63000 Clermont-Ferrand, France.ORCID 0000-0001-9465-7844
Centre National de la Recherche Scientifique · FRUniversité Clermont Auvergne · FRInserm · FRInstitut Universitaire de France · FR

Funding

Agence Nationale de la Recherche ANR-18-IDEX-001European Research Council ERC-2018-StG- 804135IDEX-ISITE (CAP-2025) NAInserm NAI-SITE project (CAP2025) NAKenneth Rainin Foundation NAMinistère de la Recherche et de la Technologie NANational program "Microbiote" from Inserm NANational Research Institute for Agriculture, Food and Environment USC-2018Valorex NA
6 · The paper itself

Abstract

The Western diet, rich in lipids and in n-6 polyunsaturated fatty acids (PUFAs), favors gut dysbiosis observed in Crohn's disease (CD). The aim of this study was to assess the effects of rebalancing the n-6/n-3 PUFA ratio in CEABAC10 transgenic mice that mimic CD. Mice in individual cages with running wheels were randomized in three diet groups for 12 weeks: high-fat diet (HFD), HFD + linseed oil (HFD-LS-O) and HFD + extruded linseed (HFD-LS-E). Then, they were orally challenged once with the Adherent-Invasive

Indexed as

Crohn DiseaseFlaxMicrobiotaAnimalsDietary SupplementsDiet, High-FatDisease Models, AnimalEscherichia coliIntestinal MucosaLinseed OilMiceMice, TransgenicLinseed Oiladherent-invasive E. colibutyrateinflammationlinseedmucosa-associated microbiota

Identifiers

PMID35682570
PMCPMC9180845
OpenAlexW4281479430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.