Evidence map›Paper›PMID 35682375›Full record

ArticleInternational journal of environmental research and public health2022

Automated Machine Learning (AutoML)-Derived Preconception Predictive Risk Model to Guide Early Intervention for Gestational Diabetes Mellitus.

Mukkesh Kumar, Li Ting Ang, Hang Png, Maisie Ng, Karen Tan, See Ling Loy, Kok Hian Tan, Jerry Kok Yen Chan, Keith M Godfrey, Shiao-Yng Chan and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Journal of clinical medicine · 2025
    Review
  4. Review
  5. Review
  6. Artificial Intelligence in Gestational Diabetes Care: A Systematic Review.Journal of diabetes science and technology · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Mukkesh KumarSingapore Institute for Clinical Sciences, Agency for Science Technology and Research, Singapore 138632, Singapore.ORCID 0000-0001-6640-4284
Li Ting AngSingapore Institute for Clinical Sciences, Agency for Science Technology and Research, Singapore 138632, Singapore.
Hang PngSingapore Institute for Clinical Sciences, Agency for Science Technology and Research, Singapore 138632, Singapore.
Maisie NgSingapore Institute for Clinical Sciences, Agency for Science Technology and Research, Singapore 138632, Singapore.
Karen TanSingapore Institute for Clinical Sciences, Agency for Science Technology and Research, Singapore 138632, Singapore.ORCID 0000-0002-7768-037X
See Ling LoyObstetrics & Gynaecology Academic Clinical Programme, Duke-NUS Medical School, Singapore 169857, Singapore.
Kok Hian TanObstetrics & Gynaecology Academic Clinical Programme, Duke-NUS Medical School, Singapore 169857, Singapore.ORCID 0000-0003-1945-0266
Jerry Kok Yen ChanObstetrics & Gynaecology Academic Clinical Programme, Duke-NUS Medical School, Singapore 169857, Singapore.
Keith M GodfreyMRC Lifecourse Epidemiology Centre, NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, University of Southampton, Southampton SO17 1BJ, UK.ORCID 0000-0002-4643-0618
Shiao-Yng ChanSingapore Institute for Clinical Sciences, Agency for Science Technology and Research, Singapore 138632, Singapore.
Yap Seng ChongSingapore Institute for Clinical Sciences, Agency for Science Technology and Research, Singapore 138632, Singapore.
Johan G ErikssonSingapore Institute for Clinical Sciences, Agency for Science Technology and Research, Singapore 138632, Singapore.
Mengling FengSaw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore 119077, Singapore.ORCID 0000-0002-5338-6248
Neerja KarnaniSingapore Institute for Clinical Sciences, Agency for Science Technology and Research, Singapore 138632, Singapore.
Agency for Science, Technology and Research · SGNational University of Singapore · SGKK Women's and Children's Hospital · SGUniversity Hospital Southampton NHS Foundation Trust · GB

Funding

Medical Research Council MC_UU_12011/4
6 · The paper itself

Abstract

The increasing prevalence of gestational diabetes mellitus (GDM) is contributing to the rising global burden of type 2 diabetes (T2D) and intergenerational cycle of chronic metabolic disorders. Primary lifestyle interventions to manage GDM, including second trimester dietary and exercise guidance, have met with limited success due to late implementation, poor adherence and generic guidelines. In this study, we aimed to build a preconception-based GDM predictor to enable early intervention. We also assessed the associations of top predictors with GDM and adverse birth outcomes. Our evolutionary algorithm-based automated machine learning (AutoML) model was implemented with data from 222 Asian multi-ethnic women in a preconception cohort study, Singapore Preconception Study of Long-Term Maternal and Child Outcomes (S-PRESTO). A stacked ensemble model with a gradient boosting classifier and linear support vector machine classifier (stochastic gradient descent training) was derived using genetic programming, achieving an excellent AUC of 0.93 based on four features (glycated hemoglobin A

Indexed as

Diabetes, GestationalDiabetes Mellitus, Type 2Premature BirthChildCohort StudiesFemaleHumansInfant, NewbornMachine LearningPregnancyRisk FactorsAsian populationsdigital healthgestational diabetes mellitusHbA1cmachine learningpreconception carepredictionpreterm birthpublic healthrisk factors

Identifiers

PMID35682375
PMCPMC9180245
OpenAlexW4281767977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.