SynthesisInternational journal of environmental research and public health2022
Cytogenetic Effects in Children Exposed to Air Pollutants: A Systematic Review and Meta-Analysis.
Synthesis in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- Effects of urban-induced mutations on ecology, evolution and health.Nature ecology & evolution · 2024Review
- Air Pollution and Primary DNA Damage among Zagreb (Croatia) Residents: A Cross-Sectional Study.Journal of xenobiotics · 2024Article
- Public Concern about Air Pollution and Related Health Outcomes on Social Media in China: An Analysis of Data from Sina Weibo (Chinese Twitter) and Air Monitoring Stations.International journal of environmental research and public health · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this systematic review and meta-analysis was to assess the association between exposure to ambient air pollutants and micronuclei (MN) frequency in children. This work was performed according to the Cochrane Collaboration and the PRISMA guidelines and recommendations. Articles published before November 2021 were identified by an advanced search on PubMed/MEDLINE, Scopus and Web of Science databases. A critical appraisal using a specific tool was conducted to assess the quality of each included study. All analyses were carried out by using the Review Manager (RevMan) 5.4 software (The Cochrane Collaboration, London, UK). One hundred and forty-five references were firstly identified, and, at the end of selection process, 13 studies met the inclusion criteria. Six studies carried out a direct evaluation through the use of air samplers, whereas the other ones accessed environmental databases (n = 2) or used other tools (n = 3). In two cases, exposure was not directly investigated, with children sampled in two different areas with well-known different levels of pollution. The overall effect size (ES) was 1.57 ((95% CI = 1.39; 1.78), p-value < 0.00001) (total evaluated subjects: 4162), which highlighted a statistically significant association between outdoor air pollution and MN frequency in children. As a high MN frequency has been associated with a number of pathological states and a higher risk of developing chronic degenerative diseases, our results should be taken into consideration by policy makers to design and implement interventions aimed at reducing the introduction of pollutants in the atmosphere as well as at minimizing the exposure extent, particularly in children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.