Evidence map›Paper›PMID 35681769›Full record

ReviewCancers2022

Proton Therapy in the Management of Pancreatic Cancer.

Jana M Kobeissi, Charles B Simone, Haibo Lin, Lara Hilal, Carla Hajj

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Jana M KobeissiDepartment of Radiation Oncology, School of Medicine, American University of Beirut Medical Center, Beirut 1107, Lebanon.ORCID 0000-0002-0266-8376
Charles B SimoneDepartment of Radiation Oncology, New York Proton Center, New York, NY 10035, USA.ORCID 0000-0002-0867-3694
Haibo LinDepartment of Radiation Oncology, New York Proton Center, New York, NY 10035, USA.
Lara HilalDepartment of Radiation Oncology, School of Medicine, American University of Beirut Medical Center, Beirut 1107, Lebanon.ORCID 0000-0002-4508-2391
Carla HajjDepartment of Radiation Oncology, New York Proton Center, New York, NY 10035, USA.
American University of Beirut Medical Center · LBMemorial Sloan Kettering Cancer Center · USNew York Proton Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Radiation therapy plays a central role in the treatment of pancreatic cancer. While generally shown to be feasible, proton irradiation, particularly when an ablative dose is planned, remains a challenge, especially due to tumor motion and the proximity to organs at risk, like the stomach, duodenum, and bowel. Clinically, standard doses of proton radiation treatment have not been shown to be statistically different from photon radiation treatment in terms of oncologic outcomes and toxicity rates as per non-randomized comparative studies. Fractionation schedules and concurrent chemotherapy combinations are yet to be optimized for proton therapy and are the subject of ongoing trials.

Indexed as

double scattering proton therapyintensity modulated proton therapypancreatic cancerpencil beam scanningproton radiation therapytoxicity

Identifiers

PMID35681769
PMCPMC9179382
OpenAlexW4281724391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.