Evidence map›Paper›PMID 35681724›Full record

ArticleCancers2022

P2X Purinergic Receptors Are Multisensory Detectors for Micro-Environmental Stimuli That Control Migration of Tumoral Endothelium.

Giorgia Scarpellino, Tullio Genova, Elisa Quarta, Carla Distasi, Marianna Dionisi, Alessandra Fiorio Pla, Luca Munaron

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. CaBiomedicines · 2025
    Review
  5. Article
  6. Article
  7. Lysosomal TRPML1 triggers global CaFrontiers in physiology · 2024
    Article
  8. Cracking the Endothelial Calcium (CaInternational journal of molecular sciences · 2023
    Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Giorgia ScarpellinoDepartment of Life Sciences & Systems Biology, University of Torino, 10123 Torino, Italy.
Tullio GenovaDepartment of Life Sciences & Systems Biology, University of Torino, 10123 Torino, Italy.ORCID 0000-0001-7824-8389
Elisa QuartaDepartment of Life Sciences & Systems Biology, University of Torino, 10123 Torino, Italy.ORCID 0000-0002-0235-6102
Carla DistasiDepartment of Pharmaceutical Sciences, University of Piemonte Orientale, 28100 Novara, Italy.ORCID 0000-0001-8815-3252
Marianna DionisiDepartment of Pharmaceutical Sciences, University of Piemonte Orientale, 28100 Novara, Italy.
Alessandra Fiorio PlaDepartment of Life Sciences & Systems Biology, University of Torino, 10123 Torino, Italy.ORCID 0000-0003-4576-1594
Luca MunaronDepartment of Life Sciences & Systems Biology, University of Torino, 10123 Torino, Italy.ORCID 0000-0001-9247-4446
University of Turin · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · IT

Funding

Italian Ministry for University and Research (MUR) 20174TB8KW
6 · The paper itself

Abstract

The tumoral microenvironment often displays peculiar features, including accumulation of extracellular ATP, hypoxia, low pH-acidosis, as well as an imbalance in zinc (Zn

Indexed as

calcium signalingcell migrationpurinergic receptorstumor-derived endothelial cells

Identifiers

PMID35681724
PMCPMC9179260
OpenAlexW4281613477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.