Evidence map›Paper›PMID 35681600›Full record

ArticleCancers2022

No Geographical Inequalities in Survival for Sarcoma Patients in France: A Reference Networks' Outcome?

Yohan Fayet, Christine Chevreau, Gauthier Decanter, Cécile Dalban, Pierre Meeus, Sébastien Carrère, Leila Haddag-Miliani, François Le Loarer, Sylvain Causeret, Daniel Orbach and 34 more

Abstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

44 authors.

Yohan FayetEMS Team-Human and Social Sciences Department, Centre Léon Bérard, 69008 Lyon, France.ORCID 0000-0002-5664-4636
Christine ChevreauICR IUCT-Oncopole, 31000 Toulouse, France.
Gauthier DecanterDepartment of Surgical Oncology, Oscar Lambret Center, 59000 Lille, France.
Cécile DalbanDepartment of Clinical Research and Innovation, Centre Léon Bérard, 69008 Lyon, France.
Pierre MeeusDepartment of Surgery, Centre Léon Bérard, 69008 Lyon, France.
Sébastien CarrèreInstitut de Recherche en Cancérologie Montpellier, INSERM U1194, 34000 Montpellier, France.
Leila Haddag-MilianiService D'imagerie Diagnostique, Institut Gustave Roussy, 94800 Villejuif, France.
François Le LoarerDepartment of Pathology, Institut Bergonié, 33000 Bordeaux, France.ORCID 0000-0001-8582-9819
Sylvain CauseretCentre Georges François Leclerc, 21000 Dijon, France.
Daniel OrbachCentre Oncologie SIREDO (Soins, Innovation et Recherche en Oncologie de l'Enfant, de l'aDOlescents et de L'adulte Jeune), Institut Curie, Université de Recherche Paris Sciences et Lettres, 75005 Paris, France.ORCID 0000-0002-2520-139X
Michelle KindRadiologue, Département D'imagerie Médicale, Institut Bergonié, 33000 Bordeaux, France.
Louis-Romée Le NailDepartment of Orthopaedic Surgery, CHU de Tours, Faculté de Médecine, Université de Tours, 37000 Tours, France.
Gwenaël FerronINSERM CRCT19 ONCO-SARC (Sarcoma Oncogenesis), Institut Claudius Regaud-Institut Universitaire du Cancer, 31000 Toulouse, France.
Hélène LabrosseCRLCC Léon Berard, Oncology Regional Network ONCO-AURA, 69008 Lyon, France.
Loïc ChaigneauDepartment of Medical Oncology, CHRU Jean Minjoz, 25000 Besançon, France.
François BertucciDepartment of Medical Oncology, Institut Paoli-Calmettes, 13009 Marseille, France.ORCID 0000-0002-0157-0959
Jean-Christophe RuzicCHU Réunion, 97410 Saint-Pierre, France.
Valérie Le Brun LyService D'oncologie Médicale, CHU Dupuytren, 87000 Limoges, France.
Fadila FarsiCRLCC Léon Berard, Oncology Regional Network ONCO-AURA, 69008 Lyon, France.
Emmanuelle BompasMedical Oncology Department, ICO, 44800 Saint Herblain, France.
Sabine NoalUCP Sarcome, Centre François Baclesse, 14000 Caen, France.
Aurore VozyDepartment of Medical Oncology, Pitié Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Institut Universitaire de Cancérologie (IUC), CLIP(2) Galilée, Sorbonne University, 75013 Paris, France.
Agnes DucoulombierCentre Antoine-Lacassagne, 06000 Nice, France.
Clément BonnetService d'Oncologie Médicale Hôpital Saint Louis, 75010 Paris, France.
Sylvie ChabaudDepartment of Clinical Research and Innovation, Centre Léon Bérard, 69008 Lyon, France.
Françoise DucimetièreEquipe EMS, Centre Léon Bérard, 69008 Lyon, France.ORCID 0000-0003-2889-685X
Camille TlemsaniService d'Oncologie Médicale, Hôpital Cochin, Institut du Cancer Paris CARPEM, Université de Paris, APHP Centre, 75014 Paris, France.ORCID 0000-0002-3342-1704
Mickaël RoparsOrthopaedic and Trauma Department, Pontchaillou University Hospital, University of Rennes 1, 35000 Rennes, France.
Olivier CollardDépartement d'Oncologie Médicale, Hôpital Privé de la Loire, 42100 Saint-Etienne, France.
Paul MichelinService D'imagerie Médicale, CHU Hopitaux de Rouen-Hopital Charles Nicolle, 76000 Rouen, France.ORCID 0000-0002-7483-4249
Justine GantzerDepartment of Medical Oncology, Strasbourg-Europe Cancer Institute (ICANS), 67033 Strasbourg, France.
Pascale Dubray-LongerasOncology Department, Centre Jean Perrin, 63011 Clermont-Ferrand, France.
Maria RiosDepartment of Medical Oncology, Cancer Institute of Lorraine-Alexis Vautrin, 54500 Vandoeuvre Les Nancy, France.
Pauline SoibinetDepartment of Hepato-Gastroenterology and Digestive Oncology, Reims University Hospital, 51000 Reims, France.
Axel Le CesneMedical Oncology, Insitut Gustave Roussy, 94800 Villejuif, France.
Florence DuffaudDepartment of Medical Oncology, CHU La Timone and Aix-Marseille Université (AMU), 13005 Marseille, France.
Marie KaranianDepartment of Pathology, Lyon University Hospital, 69008 Lyon, France.
François GouinDepartment of Surgery, Centre Léon Bérard, 69008 Lyon, France.
Raphaël TétreauMedical Imaging Center, Institut du Cancer, 34000 Montpellier, France.
Charles HonoréDepartment of Surgical Oncology, Gustave Roussy, Villejuif 94800, France.
Jean-Michel CoindreDepartment of Pathology, Institut Bergonié, 33000 Bordeaux, France.
Isabelle Ray-CoquardDepartment of Medical Oncology, Centre Leon Berard, 69008 Lyon, France.ORCID 0000-0003-2472-8306
Sylvie BonvalotDepartment of Surgical Oncology, Institut Curie, Université Paris Sciences et Lettres, 75005 Paris, France.ORCID 0000-0001-9726-9732
Jean-Yves BlayDepartment of Medical Oncology, Centre Léon Bérard, Lyon University, 69008 Lyon, France.ORCID 0000-0001-7190-120X

Funding

Fondation ARC pour la Recherche sur le Cancer PGA1*20160203865French National Cancer Institute SHSESP16-063SIRIC LYriCAN grant INCa-DGOS-Inserm_12563
6 · The paper itself

Abstract

The national reference network NETSARC+ provides remote access to specialized diagnosis and the Multidisciplinary Tumour Board (MTB) to improve the management and survival of sarcoma patients in France. The IGéAS research program aims to assess the potential of this innovative organization to address geographical inequalities in cancer management. Using the IGéAS cohort built from the nationwide NETSARC+ database, the individual, clinical, and geographical determinants of the 3-year overall survival of sarcoma patients in France were analyzed. The survival analysis was focused on patients diagnosed in 2013 (n = 2281) to ensure sufficient hindsight to collect patient follow-up. Our study included patients with bone (16.8%), soft-tissue (69%), and visceral (14.2%) sarcomas, with a median age of 61.8 years. The overall survival was not associated with geographical variables after adjustment for individual and clinical factors. The lower survival in precarious population districts [HR 1.23, 95% CI 1.02 to 1.48] in comparison to wealthy metropolitan areas (HR = 1) found in univariable analysis was due to the worst clinical presentation at diagnosis of patients. The place of residence had no impact on sarcoma patients' survival, in the context of the national organization driven by the reference network. Following previous findings, this suggests the ability of this organization to go through geographical barriers usually impeding the optimal management of cancer patients.

Indexed as

Francerare cancersreference networksremotenesssocial deprivationspatial inequalities

Identifiers

PMID35681600
PMCPMC9179906

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