Evidence map›Paper›PMID 35681571›Full record

ArticleCancers2022

Design of New Potent and Selective Thiophene-Based K

Špela Gubič, Louise Antonia Hendrickx, Xiaoyi Shi, Žan Toplak, Štefan Možina, Kenny M Van Theemsche, Ernesto Lopes Pinheiro-Junior, Steve Peigneur, Alain J Labro, Luis A Pardo and 3 more

Erratum issuedAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Špela GubičFaculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia.ORCID 0000-0002-2982-309X
Louise Antonia HendrickxCampus Gasthuisberg, University of Leuven, Toxicology and Pharmacology, Onderwijs en Navorsing 2, Herestraat 49, 3000 Leuven, Belgium.
Xiaoyi ShiAG Oncophysiology, Max-Planck Institute for Multidisciplinary Sciences, Hermann-Rein-Str. 3, 37075 Göttingen, Germany.
Žan ToplakFaculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia.
Štefan MožinaFaculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia.ORCID 0000-0002-7416-6981
Kenny M Van TheemscheLaboratory for Molecular, Cellular and Network Excitability, Department of Biomedical Sciences, University of Antwerp, 2610 Wilrijk, Belgium.
Ernesto Lopes Pinheiro-JuniorCampus Gasthuisberg, University of Leuven, Toxicology and Pharmacology, Onderwijs en Navorsing 2, Herestraat 49, 3000 Leuven, Belgium.ORCID 0000-0001-6050-8285
Steve PeigneurCampus Gasthuisberg, University of Leuven, Toxicology and Pharmacology, Onderwijs en Navorsing 2, Herestraat 49, 3000 Leuven, Belgium.ORCID 0000-0003-0504-5702
Alain J LabroLaboratory for Molecular, Cellular and Network Excitability, Department of Biomedical Sciences, University of Antwerp, 2610 Wilrijk, Belgium.ORCID 0000-0002-0871-7511
Luis A PardoAG Oncophysiology, Max-Planck Institute for Multidisciplinary Sciences, Hermann-Rein-Str. 3, 37075 Göttingen, Germany.
Jan TytgatCampus Gasthuisberg, University of Leuven, Toxicology and Pharmacology, Onderwijs en Navorsing 2, Herestraat 49, 3000 Leuven, Belgium.
Tihomir TomašičFaculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia.ORCID 0000-0002-4653-7028
Lucija Peterlin MašičFaculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia.ORCID 0000-0003-0624-8472

Funding

KU Leuven PDM/19/164Max Planck Society No. 813834-PHIONIC-H2020-MSCA-ITN-2018.Research Foundation - Flanders GOE7120N, GOC2319N, and GOA4919NResearch Foundation - Flanders Vlaanderen grant 12W7822NSlovenian Research Agency J1-9192, N1-0098, P1-0245
6 · The paper itself

Abstract

The voltage-gated potassium channel K

Indexed as

anticancer drugsantiproliferative activityapoptosisKV1.3potassium ion channels

Identifiers

PMID35681571
PMCPMC9179341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.